Rawlings DJ - Search Results

1

Efficient Enrichment of Gene-Modified Primary T Cells via CCR5-Targeted Integration of Mutant Dihydrofolate Reductase.

Paul B, Ibarra GSR, Hubbard N, Einhaus T, Astrakhan A, Rawlings DJ, Kiem HP, Peterson CW. Paul B, et al. Among authors: rawlings dj. Mol Ther Methods Clin Dev. 2018 Apr 5;9:347-357. doi: 10.1016/j.omtm.2018.04.002. eCollection 2018 Jun 15. Mol Ther Methods Clin Dev. 2018. PMID: 30038938 Free PMC article.

2

Sustained correction of B-cell development and function in a murine model of X-linked agammaglobulinemia (XLA) using retroviral-mediated gene transfer.

Yu PW, Tabuchi RS, Kato RM, Astrakhan A, Humblet-Baron S, Kipp K, Chae K, Ellmeier W, Witte ON, Rawlings DJ. Yu PW, et al. Among authors: rawlings dj. Blood. 2004 Sep 1;104(5):1281-90. doi: 10.1182/blood-2003-09-3044. Epub 2004 May 13. Blood. 2004. PMID: 15142874 Free article.

3

Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development.

Astrakhan A, Omori M, Nguyen T, Becker-Herman S, Iseki M, Aye T, Hudkins K, Dooley J, Farr A, Alpers CE, Ziegler SF, Rawlings DJ. Astrakhan A, et al. Among authors: rawlings dj. Nat Immunol. 2007 May;8(5):522-31. doi: 10.1038/ni1452. Epub 2007 Apr 1. Nat Immunol. 2007. PMID: 17401368

4

Wiskott-Aldrich syndrome protein is required for homeostasis and function of invariant NKT cells.

Astrakhan A, Ochs HD, Rawlings DJ. Astrakhan A, et al. Among authors: rawlings dj. J Immunol. 2009 Jun 15;182(12):7370-80. doi: 10.4049/jimmunol.0804256. J Immunol. 2009. PMID: 19494259 Free PMC article.

5

B cell-specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia.

Kerns HM, Ryu BY, Stirling BV, Sather BD, Astrakhan A, Humblet-Baron S, Liggitt D, Rawlings DJ. Kerns HM, et al. Among authors: rawlings dj. Blood. 2010 Mar 18;115(11):2146-55. doi: 10.1182/blood-2009-09-241869. Epub 2010 Jan 21. Blood. 2010. PMID: 20093406 Free PMC article.

6

Development of B-lineage predominant lentiviral vectors for use in genetic therapies for B cell disorders.

Sather BD, Ryu BY, Stirling BV, Garibov M, Kerns HM, Humblet-Baron S, Astrakhan A, Rawlings DJ. Sather BD, et al. Among authors: rawlings dj. Mol Ther. 2011 Mar;19(3):515-25. doi: 10.1038/mt.2010.259. Epub 2010 Dec 7. Mol Ther. 2011. PMID: 21139568 Free PMC article.

7

Novel reporter systems for facile evaluation of I-SceI-mediated genome editing.

Muñoz NM, Beard BC, Ryu BY, Luche RM, Trobridge GD, Rawlings DJ, Scharenberg AM, Kiem HP. Muñoz NM, et al. Among authors: rawlings dj. Nucleic Acids Res. 2012 Jan;40(2):e14. doi: 10.1093/nar/gkr897. Epub 2011 Nov 21. Nucleic Acids Res. 2012. PMID: 22110042 Free PMC article.

8

Ubiquitous high-level gene expression in hematopoietic lineages provides effective lentiviral gene therapy of murine Wiskott-Aldrich syndrome.

Astrakhan A, Sather BD, Ryu BY, Khim S, Singh S, Humblet-Baron S, Ochs HD, Miao CH, Rawlings DJ. Astrakhan A, et al. Among authors: rawlings dj. Blood. 2012 May 10;119(19):4395-407. doi: 10.1182/blood-2011-03-340711. Epub 2012 Mar 19. Blood. 2012. PMID: 22431569 Free PMC article.

9

Coupling endonucleases with DNA end-processing enzymes to drive gene disruption.

Certo MT, Gwiazda KS, Kuhar R, Sather B, Curinga G, Mandt T, Brault M, Lambert AR, Baxter SK, Jacoby K, Ryu BY, Kiem HP, Gouble A, Paques F, Rawlings DJ, Scharenberg AM. Certo MT, et al. Among authors: rawlings dj. Nat Methods. 2012 Oct;9(10):973-5. doi: 10.1038/nmeth.2177. Epub 2012 Sep 2. Nat Methods. 2012. PMID: 22941364 Free PMC article.

10

Intravenous injection of a foamy virus vector to correct canine SCID-X1.

Burtner CR, Beard BC, Kennedy DR, Wohlfahrt ME, Adair JE, Trobridge GD, Scharenberg AM, Torgerson TR, Rawlings DJ, Felsburg PJ, Kiem HP. Burtner CR, et al. Among authors: rawlings dj. Blood. 2014 Jun 5;123(23):3578-84. doi: 10.1182/blood-2013-11-538926. Epub 2014 Mar 18. Blood. 2014. PMID: 24642749 Free PMC article.

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