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Phase 1, Dose Escalation, Nonrandomized, Open-Label, Clinical Trial Evaluating the Safety and Preliminary Efficacy of Allogenic Adipose-Derived Mesenchymal Stem Cells for Recurrent Glioblastoma: A Clinical Trial Protocol.
Ramos-Fresnedo A, Al-Kharboosh R, Twohy EL, Basil AN, Szymkiewicz EC, Zubair AC, Trifiletti DM, Durand N, Dickson DW, Middlebrooks EH, Abarbanel DN, Tzeng SY, Almeida JP, Chaichana KL, Green JJ, Sherman WJ, Quiñones-Hinojosa A. Ramos-Fresnedo A, et al. Among authors: al kharboosh r. Neurosurg Pract. 2023 Dec;4(4):e00062. Epub 2023 Oct 13. Neurosurg Pract. 2023. PMID: 38464470 Free PMC article.
TREM2 mediates MHCII-associated CD4+ T-cell response against gliomas.
Zheng J, Wang L, Zhao S, Zhang W, Chang Y, Bosco DB, Huang T, Dheer A, Gao S, Xu S, Ayasoufi K, Al-Kharboosh R, Qi F, Xie M, Johnson AJ, Dong H, Quiñones-Hinojosa A, Wu LJ. Zheng J, et al. Among authors: al kharboosh r. Neuro Oncol. 2024 May 3;26(5):811-825. doi: 10.1093/neuonc/noad214. Neuro Oncol. 2024. PMID: 37941134
TREM2 mediates MHCII-associated CD4+ T cell response against gliomas.
Zheng J, Wang L, Zhao S, Zhang W, Chang Y, Dheer A, Gao S, Xu S, Ayasoufi K, Al-Kharboosh R, Xie M, Johnson AJ, Dong H, Quiñones-Hinojosa A, Wu LJ. Zheng J, et al. Among authors: al kharboosh r. bioRxiv [Preprint]. 2023 Apr 6:2023.04.05.535697. doi: 10.1101/2023.04.05.535697. bioRxiv. 2023. PMID: 37066234 Free PMC article. Updated. Preprint.
Poly(ethylene glycol)-Poly(beta-amino ester)-Based Nanoparticles for Suicide Gene Therapy Enhance Brain Penetration and Extend Survival in a Preclinical Human Glioblastoma Orthotopic Xenograft Model.
Kim J, Mondal SK, Tzeng SY, Rui Y, Al-Kharboosh R, Kozielski KK, Bhargav AG, Garcia CA, Quiñones-Hinojosa A, Green JJ. Kim J, et al. Among authors: al kharboosh r. ACS Biomater Sci Eng. 2020 May 11;6(5):2943-2955. doi: 10.1021/acsbiomaterials.0c00116. Epub 2020 Apr 17. ACS Biomater Sci Eng. 2020. PMID: 33463272 Free PMC article.
Alpha 1-antichymotrypsin contributes to stem cell characteristics and enhances tumorigenicity of glioblastoma.
Lara-Velazquez M, Zarco N, Carrano A, Phillipps J, Norton ES, Schiapparelli P, Al-Kharboosh R, Rincon-Torroella J, Jeanneret S, Corona T, Segovia J, Jentoft ME, Chaichana KL, Asmann YW, Quiñones-Hinojosa A, Guerrero-Cazares H. Lara-Velazquez M, et al. Among authors: al kharboosh r. Neuro Oncol. 2021 Apr 12;23(4):599-610. doi: 10.1093/neuonc/noaa264. Neuro Oncol. 2021. PMID: 33249487 Free PMC article.
Inflammatory Mediators in Glioma Microenvironment Play a Dual Role in Gliomagenesis and Mesenchymal Stem Cell Homing: Implication for Cellular Therapy.
Al-Kharboosh R, ReFaey K, Lara-Velazquez M, Grewal SS, Imitola J, Quiñones-Hinojosa A. Al-Kharboosh R, et al. Mayo Clin Proc Innov Qual Outcomes. 2020 Aug 5;4(4):443-459. doi: 10.1016/j.mayocpiqo.2020.04.006. eCollection 2020 Aug. Mayo Clin Proc Innov Qual Outcomes. 2020. PMID: 32793872 Free PMC article. Review.
Adipose-Derived Biogenic Nanoparticles for Suppression of Inflammation.
Tian M, Ticer T, Wang Q, Walker S, Pham A, Suh A, Busatto S, Davidovich I, Al-Kharboosh R, Lewis-Tuffin L, Ji B, Quinones-Hinojosa A, Talmon Y, Shapiro S, Rückert F, Wolfram J. Tian M, et al. Among authors: al kharboosh r. Small. 2020 Mar;16(10):e1904064. doi: 10.1002/smll.201904064. Epub 2020 Feb 18. Small. 2020. PMID: 32067382
Cancer-selective nanoparticles for combinatorial siRNA delivery to primary human GBM in vitro and in vivo.
Kozielski KL, Ruiz-Valls A, Tzeng SY, Guerrero-Cázares H, Rui Y, Li Y, Vaughan HJ, Gionet-Gonzales M, Vantucci C, Kim J, Schiapparelli P, Al-Kharboosh R, Quiñones-Hinojosa A, Green JJ. Kozielski KL, et al. Among authors: al kharboosh r. Biomaterials. 2019 Jul;209:79-87. doi: 10.1016/j.biomaterials.2019.04.020. Epub 2019 Apr 12. Biomaterials. 2019. PMID: 31026613 Free PMC article.
The Study of Brain Tumor Stem Cell Invasion.
Al-Kharboosh R, Lara-Velazquez M, Prieto L, Sarabia-Estrada R, Quiñones-Hinojosa A. Al-Kharboosh R, et al. Methods Mol Biol. 2019;1869:105-116. doi: 10.1007/978-1-4939-8805-1_10. Methods Mol Biol. 2019. PMID: 30324518 Free PMC article.
13 results