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Synthesis and antifungal activities of miltefosine analogs.
Ravu RR, Chen YL, Jacob MR, Pan X, Agarwal AK, Khan SI, Heitman J, Clark AM, Li XC. Ravu RR, et al. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4828-31. doi: 10.1016/j.bmcl.2013.06.096. Epub 2013 Jul 6. Bioorg Med Chem Lett. 2013. PMID: 23891181 Free PMC article.
Two plant-derived aporphinoid alkaloids exert their antifungal activity by disrupting mitochondrial iron-sulfur cluster biosynthesis.
Tripathi SK, Xu T, Feng Q, Avula B, Shi X, Pan X, Mask MM, Baerson SR, Jacob MR, Ravu RR, Khan SI, Li XC, Khan IA, Clark AM, Agarwal AK. Tripathi SK, et al. Among authors: ravu rr. J Biol Chem. 2017 Oct 6;292(40):16578-16593. doi: 10.1074/jbc.M117.781773. Epub 2017 Aug 18. J Biol Chem. 2017. PMID: 28821607 Free PMC article.
UPLC-MS-ELSD-PDA as a powerful dereplication tool to facilitate compound identification from small-molecule natural product libraries.
Yang J, Liang Q, Wang M, Jeffries C, Smithson D, Tu Y, Boulos N, Jacob MR, Shelat AA, Wu Y, Ravu RR, Gilbertson R, Avery MA, Khan IA, Walker LA, Guy RK, Li XC. Yang J, et al. Among authors: ravu rr. J Nat Prod. 2014 Apr 25;77(4):902-9. doi: 10.1021/np4009706. Epub 2014 Mar 11. J Nat Prod. 2014. PMID: 24617915 Free PMC article.