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Optogenetic control of protein binding using light-switchable nanobodies.
Gil AA, Carrasco-López C, Zhu L, Zhao EM, Ravindran PT, Wilson MZ, Goglia AG, Avalos JL, Toettcher JE. Gil AA, et al. Among authors: ravindran pt. Nat Commun. 2020 Aug 13;11(1):4044. doi: 10.1038/s41467-020-17836-8. Nat Commun. 2020. PMID: 32792536 Free PMC article.
Lighting Up Cancer Dynamics.
Ravindran PT, Wilson MZ. Ravindran PT, et al. Trends Cancer. 2018 Oct;4(10):657-659. doi: 10.1016/j.trecan.2018.06.001. Epub 2018 Sep 25. Trends Cancer. 2018. PMID: 30292348
Unraveling the Mechanism of a LOV Domain Optogenetic Sensor: A Glutamine Lever Induces Unfolding of the Jα Helix.
Iuliano JN, Collado JT, Gil AA, Ravindran PT, Lukacs A, Shin S, Woroniecka HA, Adamczyk K, Aramini JM, Edupuganti UR, Hall CR, Greetham GM, Sazanovich IV, Clark IP, Daryaee T, Toettcher JE, French JB, Gardner KH, Simmerling CL, Meech SR, Tonge PJ. Iuliano JN, et al. Among authors: ravindran pt. ACS Chem Biol. 2020 Oct 16;15(10):2752-2765. doi: 10.1021/acschembio.0c00543. Epub 2020 Sep 18. ACS Chem Biol. 2020. PMID: 32880430 Free PMC article.
Stress ball morphogenesis: How the lizard builds its lung.
Palmer MA, Nerger BA, Goodwin K, Sudhakar A, Lemke SB, Ravindran PT, Toettcher JE, Košmrlj A, Nelson CM. Palmer MA, et al. Among authors: ravindran pt. Sci Adv. 2021 Dec 24;7(52):eabk0161. doi: 10.1126/sciadv.abk0161. Epub 2021 Dec 22. Sci Adv. 2021. PMID: 34936466 Free PMC article.
Measuring nonhomologous end-joining, homologous recombination and alternative end-joining simultaneously at an endogenous locus in any transfectable human cell.
Hussain SS, Majumdar R, Moore GM, Narang H, Buechelmaier ES, Bazil MJ, Ravindran PT, Leeman JE, Li Y, Jalan M, Anderson KS, Farina A, Soni R, Mohibullah N, Hamzic E, Rong-Mullins X, Sifuentes C, Damerla RR, Viale A, Powell SN, Higginson DS. Hussain SS, et al. Among authors: ravindran pt. Nucleic Acids Res. 2021 Jul 21;49(13):e74. doi: 10.1093/nar/gkab262. Nucleic Acids Res. 2021. PMID: 33877327 Free PMC article.
Human papillomavirus 16 promotes microhomology-mediated end-joining.
Leeman JE, Li Y, Bell A, Hussain SS, Majumdar R, Rong-Mullins X, Blecua P, Damerla R, Narang H, Ravindran PT, Lee NY, Riaz N, Powell SN, Higginson DS. Leeman JE, et al. Among authors: ravindran pt. Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21573-21579. doi: 10.1073/pnas.1906120116. Epub 2019 Oct 7. Proc Natl Acad Sci U S A. 2019. PMID: 31591214 Free PMC article.
Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells.
Goyal Y, Busch GT, Pillai M, Li J, Boe RH, Grody EI, Chelvanambi M, Dardani IP, Emert B, Bodkin N, Braun J, Fingerman D, Kaur A, Jain N, Ravindran PT, Mellis IA, Kiani K, Alicea GM, Fane ME, Ahmed SS, Li H, Chen Y, Chai C, Kaster J, Witt RG, Lazcano R, Ingram DR, Johnson SB, Wani K, Dunagin MC, Lazar AJ, Weeraratna AT, Wargo JA, Herlyn M, Raj A. Goyal Y, et al. Among authors: ravindran pt. Nature. 2023 Aug;620(7974):651-659. doi: 10.1038/s41586-023-06342-8. Epub 2023 Jul 19. Nature. 2023. PMID: 37468627 Free PMC article.