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SIRT6 enhances oxidative phosphorylation in breast cancer and promotes mammary tumorigenesis in mice.
Becherini P, Caffa I, Piacente F, Damonte P, Vellone VG, Passalacqua M, Benzi A, Bonfiglio T, Reverberi D, Khalifa A, Ghanem M, Guijarro A, Tagliafico L, Sucameli M, Persia A, Monacelli F, Cea M, Bruzzone S, Ravera S, Nencioni A. Becherini P, et al. Among authors: ravera s. Cancer Metab. 2021 Jan 22;9(1):6. doi: 10.1186/s40170-021-00240-1. Cancer Metab. 2021. PMID: 33482921 Free PMC article.
IGF1 regulates PKM2 function through Akt phosphorylation.
Salani B, Ravera S, Amaro A, Salis A, Passalacqua M, Millo E, Damonte G, Marini C, Pfeffer U, Sambuceti G, Cordera R, Maggi D. Salani B, et al. Among authors: ravera s. Cell Cycle. 2015;14(10):1559-67. doi: 10.1080/15384101.2015.1026490. Cell Cycle. 2015. PMID: 25790097 Free PMC article.
Glutathione-mediated antioxidant response and aerobic metabolism: two crucial factors involved in determining the multi-drug resistance of high-risk neuroblastoma.
Colla R, Izzotti A, De Ciucis C, Fenoglio D, Ravera S, Speciale A, Ricciarelli R, Furfaro AL, Pulliero A, Passalacqua M, Traverso N, Pronzato MA, Domenicotti C, Marengo B. Colla R, et al. Among authors: ravera s. Oncotarget. 2016 Oct 25;7(43):70715-70737. doi: 10.18632/oncotarget.12209. Oncotarget. 2016. PMID: 27683112 Free PMC article.
Pharmacological Sirt6 inhibition improves glucose tolerance in a type 2 diabetes mouse model.
Sociali G, Magnone M, Ravera S, Damonte P, Vigliarolo T, Von Holtey M, Vellone VG, Millo E, Caffa I, Cea M, Parenti MD, Del Rio A, Murone M, Mostoslavsky R, Grozio A, Nencioni A, Bruzzone S. Sociali G, et al. Among authors: ravera s. FASEB J. 2017 Jul;31(7):3138-3149. doi: 10.1096/fj.201601294R. Epub 2017 Apr 6. FASEB J. 2017. PMID: 28386046 Free PMC article.
This study represents the first in vivo study of a SIRT6 inhibitor and provides the proof-of-concept that targeting SIRT6 may be a viable strategy for improving glycemic control in T2DM.-Sociali, G., Magnone, M., Ravera, S., Damonte, P., Vigliarolo, T., Von Holtey, …
This study represents the first in vivo study of a SIRT6 inhibitor and provides the proof-of-concept that targeting SIRT6 may be a viable st …
Nicotinic Acid Phosphoribosyltransferase Regulates Cancer Cell Metabolism, Susceptibility to NAMPT Inhibitors, and DNA Repair.
Piacente F, Caffa I, Ravera S, Sociali G, Passalacqua M, Vellone VG, Becherini P, Reverberi D, Monacelli F, Ballestrero A, Odetti P, Cagnetta A, Cea M, Nahimana A, Duchosal M, Bruzzone S, Nencioni A. Piacente F, et al. Among authors: ravera s. Cancer Res. 2017 Jul 15;77(14):3857-3869. doi: 10.1158/0008-5472.CAN-16-3079. Epub 2017 May 15. Cancer Res. 2017. PMID: 28507103
Glibenclamide Mimics Metabolic Effects of Metformin in H9c2 Cells.
Salani B, Ravera S, Fabbi P, Garibaldi S, Passalacqua M, Brunelli C, Maggi D, Cordera R, Ameri P. Salani B, et al. Among authors: ravera s. Cell Physiol Biochem. 2017;43(3):879-890. doi: 10.1159/000481638. Epub 2017 Sep 28. Cell Physiol Biochem. 2017. PMID: 28954268 Free article.
255 results