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Targeted purification development enabled by computational biophysical modeling.
Biotechnol Prog. 2015 Jan-Feb;31(1):154-64. doi: 10.1002/btpr.2023. Epub 2014 Dec 19.
Biotechnol Prog. 2015.
PMID: 25482184
Insulin purification-Innovation continuum via synthesis of fundamentals, technology, and modeling.
Roush D, Iammarino M, Chmielowski R, Insaidoo F, McCoy MA, Ortigosa A, Rauscher M.
Roush D, et al. Among authors: rauscher m.
Biotechnol Bioeng. 2023 May 18. doi: 10.1002/bit.28427. Online ahead of print.
Biotechnol Bioeng. 2023.
PMID: 37200159
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Prediction of lab and manufacturing scale chromatography performance using mini-columns and mechanistic modeling.
Benner SW, Welsh JP, Rauscher MA, Pollard JM.
Benner SW, et al. Among authors: rauscher ma.
J Chromatogr A. 2019 May 24;1593:54-62. doi: 10.1016/j.chroma.2019.01.063. Epub 2019 Jan 24.
J Chromatogr A. 2019.
PMID: 30739757
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Cationic polymer precipitation for enhanced impurity removal in downstream processing.
Li Z, Chen J, Martinez-Fonts K, Rauscher M, Rivera S, Welsh J, Kandula S.
Li Z, et al.
Biotechnol Bioeng. 2023 Jul;120(7):1902-1913. doi: 10.1002/bit.28416. Epub 2023 May 6.
Biotechnol Bioeng. 2023.
PMID: 37148495
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Predicting Antibody Developability Profiles Through Early Stage Discovery Screening.
Bailly M, Mieczkowski C, Juan V, Metwally E, Tomazela D, Baker J, Uchida M, Kofman E, Raoufi F, Motlagh S, Yu Y, Park J, Raghava S, Welsh J, Rauscher M, Raghunathan G, Hsieh M, Chen YL, Nguyen HT, Nguyen N, Cipriano D, Fayadat-Dilman L.
Bailly M, et al.
MAbs. 2020 Jan-Dec;12(1):1743053. doi: 10.1080/19420862.2020.1743053.
MAbs. 2020.
PMID: 32249670
Free PMC article.
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Changes in renal and systemic hemodynamics after NO-synthase inhibition in males with family history of hypertension.
Berger ED, Bader BD, Rüb N, Rauscher MA, Rebenschütz I, Gaber OC, Enderle MD, Risler T, Erley CM.
Berger ED, et al. Among authors: rauscher ma.
Kidney Blood Press Res. 2002;25(1):42-9. doi: 10.1159/000049434.
Kidney Blood Press Res. 2002.
PMID: 11834876
Clinical Trial.
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