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A powerful global test for spliceQTL effects.
de Menezes RX, Rauschenberger A; BIOS Consortium; 't Hoen PAC, Jonker MA. de Menezes RX, et al. Among authors: rauschenberger a. Biom J. 2023 Jan;65(1):e2100123. doi: 10.1002/bimj.202100123. Epub 2022 Jul 11. Biom J. 2023. PMID: 35818126
Predictive and interpretable models via the stacked elastic net.
Rauschenberger A, Glaab E, van de Wiel MA. Rauschenberger A, et al. Bioinformatics. 2021 Aug 4;37(14):2012-2016. doi: 10.1093/bioinformatics/btaa535. Bioinformatics. 2021. PMID: 32437519 Free PMC article.
It has a mixing parameter to weight between ridge and lasso regularization. Instead of selecting one weighting by tuning, we combine multiple weightings by stacking. We do this in a way that increases predictivity without sacrificing interpretability. ...
It has a mixing parameter to weight between ridge and lasso regularization. Instead of selecting one weighting by tuning, we combine …
Predicting correlated outcomes from molecular data.
Rauschenberger A, Glaab E. Rauschenberger A, et al. Bioinformatics. 2021 Nov 5;37(21):3889-3895. doi: 10.1093/bioinformatics/btab576. Bioinformatics. 2021. PMID: 34358294 Free PMC article.
RESULTS: Our flexible approach leads to predictive and interpretable models in high-dimensional settings, with a single estimate for each input-output effect. In the simulation, we compare the predictive performance of several state-of-the-art methods for multivariate regr …
RESULTS: Our flexible approach leads to predictive and interpretable models in high-dimensional settings, with a single estimate for …
Ten quick tips for biomarker discovery and validation analyses using machine learning.
Diaz-Uriarte R, Gómez de Lope E, Giugno R, Fröhlich H, Nazarov PV, Nepomuceno-Chamorro IA, Rauschenberger A, Glaab E. Diaz-Uriarte R, et al. Among authors: rauschenberger a. PLoS Comput Biol. 2022 Aug 11;18(8):e1010357. doi: 10.1371/journal.pcbi.1010357. eCollection 2022 Aug. PLoS Comput Biol. 2022. PMID: 35951526 Free PMC article. No abstract available.
Publisher Correction: Age at onset as stratifier in idiopathic Parkinson's disease - effect of ageing and polygenic risk score on clinical phenotypes.
Pavelka L, Rauschenberger A, Landoulsi Z, Pachchek S, May P, Glaab E, Krüger R; NCER-PD Consortium. Pavelka L, et al. Among authors: rauschenberger a. NPJ Parkinsons Dis. 2022 Sep 2;8(1):112. doi: 10.1038/s41531-022-00378-9. NPJ Parkinsons Dis. 2022. PMID: 36056009 Free PMC article. No abstract available.
22 results