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Dynamic landscape of pancreatic carcinogenesis reveals early molecular networks of malignancy.
Kong B, Bruns P, Behler NA, Chang L, Schlitter AM, Cao J, Gewies A, Ruland J, Fritzsche S, Valkovskaya N, Jian Z, Regel I, Raulefs S, Irmler M, Beckers J, Friess H, Erkan M, Mueller NS, Roth S, Hackert T, Esposito I, Theis FJ, Kleeff J, Michalski CW. Kong B, et al. Among authors: raulefs s. Gut. 2018 Jan;67(1):146-156. doi: 10.1136/gutjnl-2015-310913. Epub 2016 Sep 19. Gut. 2018. PMID: 27646934
Energy metabolism and proliferation in pancreatic carcinogenesis.
Regel I, Kong B, Raulefs S, Erkan M, Michalski CW, Hartel M, Kleeff J. Regel I, et al. Among authors: raulefs s. Langenbecks Arch Surg. 2012 Apr;397(4):507-12. doi: 10.1007/s00423-012-0933-9. Epub 2012 Mar 20. Langenbecks Arch Surg. 2012. PMID: 22430298 Review.
A subset of metastatic pancreatic ductal adenocarcinomas depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling.
Kong B, Wu W, Cheng T, Schlitter AM, Qian C, Bruns P, Jian Z, Jäger C, Regel I, Raulefs S, Behler N, Irmler M, Beckers J, Friess H, Erkan M, Siveke JT, Tannapfel A, Hahn SA, Theis FJ, Esposito I, Kleeff J, Michalski CW. Kong B, et al. Among authors: raulefs s. Gut. 2016 Apr;65(4):647-57. doi: 10.1136/gutjnl-2014-307616. Epub 2015 Jan 19. Gut. 2016. PMID: 25601637
Ring1b-dependent epigenetic remodelling is an essential prerequisite for pancreatic carcinogenesis.
Benitz S, Straub T, Mahajan UM, Mutter J, Czemmel S, Unruh T, Wingerath B, Deubler S, Fahr L, Cheng T, Nahnsen S, Bruns P, Kong B, Raulefs S, Ceyhan GO, Mayerle J, Steiger K, Esposito I, Kleeff J, Michalski CW, Regel I. Benitz S, et al. Among authors: raulefs s. Gut. 2019 Nov;68(11):2007-2018. doi: 10.1136/gutjnl-2018-317208. Epub 2019 Apr 6. Gut. 2019. PMID: 30954952
mTORC1 and mTORC2 Converge on the Arp2/3 Complex to Promote KrasG12D-Induced Acinar-to-Ductal Metaplasia and Early Pancreatic Carcinogenesis.
Zhao Y, Schoeps B, Yao D, Zhang Z, Schuck K, Tissen V, Jäger C, Schlitter AM, van der Kammen R, Ludwig C, D'Haese JG, Raulefs S, Maeritz N, Shen S, Zou X, Krüger A, Kleeff J, Michalski CW, Friess H, Innocenti M, Kong B. Zhao Y, et al. Among authors: raulefs s. Gastroenterology. 2021 Apr;160(5):1755-1770.e17. doi: 10.1053/j.gastro.2020.12.061. Epub 2021 Jan 1. Gastroenterology. 2021. PMID: 33388318
Next-generation sequencing reveals novel differentially regulated mRNAs, lncRNAs, miRNAs, sdRNAs and a piRNA in pancreatic cancer.
Müller S, Raulefs S, Bruns P, Afonso-Grunz F, Plötner A, Thermann R, Jäger C, Schlitter AM, Kong B, Regel I, Roth WK, Rotter B, Hoffmeier K, Kahl G, Koch I, Theis FJ, Kleeff J, Winter P, Michalski CW. Müller S, et al. Among authors: raulefs s. Mol Cancer. 2015 Apr 25;14:94. doi: 10.1186/s12943-015-0358-5. Mol Cancer. 2015. PMID: 25910082 Free PMC article.
24 results