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Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis.
Lei L, Bruneau A, El Mourabit H, Guégan J, Folseraas T, Lemoinne S, Karlsen TH, Hoareau B, Morichon R, Gonzalez-Sanchez E, Goumard C, Ratziu V, Charbord P, Gautheron J, Tacke F, Jaffredo T, Cadoret A, Housset C. Lei L, et al. Among authors: ratziu v. Hepatology. 2022 Nov;76(5):1360-1375. doi: 10.1002/hep.32456. Epub 2022 Mar 29. Hepatology. 2022. PMID: 35278227 Free article.
The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans.
Benhamed F, Denechaud PD, Lemoine M, Robichon C, Moldes M, Bertrand-Michel J, Ratziu V, Serfaty L, Housset C, Capeau J, Girard J, Guillou H, Postic C. Benhamed F, et al. Among authors: ratziu v. J Clin Invest. 2012 Jun;122(6):2176-94. doi: 10.1172/JCI41636. Epub 2012 May 1. J Clin Invest. 2012. PMID: 22546860 Free PMC article. Clinical Trial.
Non-alcoholic fatty liver - perhaps not so benign.
Adams LA, Ratziu V. Adams LA, et al. Among authors: ratziu v. J Hepatol. 2015 May;62(5):1002-4. doi: 10.1016/j.jhep.2015.02.005. Epub 2015 Feb 12. J Hepatol. 2015. PMID: 25681555 Free article. No abstract available.
A randomized, placebo-controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis.
Friedman SL, Ratziu V, Harrison SA, Abdelmalek MF, Aithal GP, Caballeria J, Francque S, Farrell G, Kowdley KV, Craxi A, Simon K, Fischer L, Melchor-Khan L, Vest J, Wiens BL, Vig P, Seyedkazemi S, Goodman Z, Wong VW, Loomba R, Tacke F, Sanyal A, Lefebvre E. Friedman SL, et al. Among authors: ratziu v. Hepatology. 2018 May;67(5):1754-1767. doi: 10.1002/hep.29477. Epub 2018 Jan 29. Hepatology. 2018. PMID: 28833331 Free PMC article. Clinical Trial.
404 results