Ratner ES - Search Results

1

Transforming Growth Factor Beta and Epithelial to Mesenchymal Transition Alter Homologous Recombination Repair Gene Expression and Sensitize BRCA Wild-Type Ovarian Cancer Cells to Olaparib.

Roberts CM, Rojas-Alexandre M, Hanna RE, Lin ZP, Ratner ES. Roberts CM, et al. Among authors: ratner es. Cancers (Basel). 2023 Aug 1;15(15):3919. doi: 10.3390/cancers15153919. Cancers (Basel). 2023. PMID: 37568736 Free PMC article.

2

Poly (ADP-ribose) polymerase inhibitors: on the horizon of tailored and personalized therapies for epithelial ovarian cancer.

Ratner ES, Sartorelli AC, Lin ZP. Ratner ES, et al. Curr Opin Oncol. 2012 Sep;24(5):564-71. doi: 10.1097/CCO.0b013e3283564230. Curr Opin Oncol. 2012. PMID: 22759740 Free PMC article. Review.

3

Triapine disrupts CtIP-mediated homologous recombination repair and sensitizes ovarian cancer cells to PARP and topoisomerase inhibitors.

Lin ZP, Ratner ES, Whicker ME, Lee Y, Sartorelli AC. Lin ZP, et al. Among authors: ratner es. Mol Cancer Res. 2014 Mar;12(3):381-393. doi: 10.1158/1541-7786.MCR-13-0480. Epub 2014 Jan 10. Mol Cancer Res. 2014. PMID: 24413181 Free PMC article.

4

Distinct mechanisms of cell-kill by triapine and its terminally dimethylated derivative Dp44mT due to a loss or gain of activity of their copper(II) complexes.

Ishiguro K, Lin ZP, Penketh PG, Shyam K, Zhu R, Baumann RP, Zhu YL, Sartorelli AC, Rutherford TJ, Ratner ES. Ishiguro K, et al. Among authors: ratner es. Biochem Pharmacol. 2014 Oct 1;91(3):312-22. doi: 10.1016/j.bcp.2014.08.006. Epub 2014 Aug 15. Biochem Pharmacol. 2014. PMID: 25130544 Free PMC article.

5

Triapine potentiates platinum-based combination therapy by disruption of homologous recombination repair.

Ratner ES, Zhu YL, Penketh PG, Berenblum J, Whicker ME, Huang PH, Lee Y, Ishiguro K, Zhu R, Sartorelli AC, Lin ZP. Ratner ES, et al. Br J Cancer. 2016 Mar 29;114(7):777-86. doi: 10.1038/bjc.2016.54. Epub 2016 Mar 10. Br J Cancer. 2016. PMID: 26964031 Free PMC article.

6

Cataloging antineoplastic agents according to their effectiveness against platinum-resistant and platinum-sensitive ovarian carcinoma cell lines.

Ishiguro K, Zhu YL, Lin ZP, Penketh PG, Shyam K, Zhu R, Baumann RP, Sartorelli AC, Rutherford TJ, Ratner ES. Ishiguro K, et al. Among authors: ratner es. J Transl Sci. 2016;2(2):117-124. doi: 10.15761/JTS.1000127. Epub 2016 Mar 5. J Transl Sci. 2016. PMID: 27076919 Free PMC article.

7

MK-2206 sensitizes BRCA-deficient epithelial ovarian adenocarcinoma to cisplatin and olaparib.

Whicker ME, Lin ZP, Hanna R, Sartorelli AC, Ratner ES. Whicker ME, et al. Among authors: ratner es. BMC Cancer. 2016 Jul 27;16:550. doi: 10.1186/s12885-016-2598-1. BMC Cancer. 2016. PMID: 27465688 Free PMC article.

8

Targeting Cyclin-Dependent Kinases for Treatment of Gynecologic Cancers.

Lin ZP, Zhu YL, Ratner ES. Lin ZP, et al. Among authors: ratner es. Front Oncol. 2018 Aug 8;8:303. doi: 10.3389/fonc.2018.00303. eCollection 2018. Front Oncol. 2018. PMID: 30135856 Free PMC article. Review.

9

Combination of triapine, olaparib, and cediranib suppresses progression of BRCA-wild type and PARP inhibitor-resistant epithelial ovarian cancer.

Lin ZP, Zhu YL, Lo YC, Moscarelli J, Xiong A, Korayem Y, Huang PH, Giri S, LoRusso P, Ratner ES. Lin ZP, et al. Among authors: ratner es. PLoS One. 2018 Nov 16;13(11):e0207399. doi: 10.1371/journal.pone.0207399. eCollection 2018. PLoS One. 2018. PMID: 30444904 Free PMC article.

10

In silico screening identifies a novel small molecule inhibitor that counteracts PARP inhibitor resistance in ovarian cancer.

Lin ZP, Al Zouabi NN, Xu ML, Bowen NE, Wu TL, Lavi ES, Huang PH, Zhu YL, Kim B, Ratner ES. Lin ZP, et al. Among authors: ratner es. Sci Rep. 2021 Apr 13;11(1):8042. doi: 10.1038/s41598-021-87325-5. Sci Rep. 2021. PMID: 33850183 Free PMC article.

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