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Page 1
Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment.
Ma J, Al Moussawi K, Lou H, Chan HF, Wang Y, Chadwick J, Phetsouphanh C, Slee EA, Zhong S, Leissing TM, Roth A, Qin X, Chen S, Yin J, Ratnayaka I, Hu Y, Louphrasitthiphol P, Taylor L, Bettencourt PJG, Muers M, Greaves DR, McShane H, Goldin R, Soilleux EJ, Coleman ML, Ratcliffe PJ, Lu X. Ma J, et al. Among authors: ratnayaka i. Proc Natl Acad Sci U S A. 2024 Mar 5;121(10):e2309957121. doi: 10.1073/pnas.2309957121. Epub 2024 Feb 29. Proc Natl Acad Sci U S A. 2024. PMID: 38422022 Free PMC article.
Corrigendum: MEF2 transcription factors are key regulators of sprouting angiogenesis.
Sacilotto N, Chouliaras KM, Nikitenko LL, Lu YW, Fritzsche M, Wallace MD, Nornes S, García-Moreno F, Payne S, Bridges E, Liu K, Biggs D, Ratnayaka I, Herbert SP, Molnár Z, Harris AL, Davies B, Bond GL, Bou-Gharios G, Schwarz JJ, De Val S. Sacilotto N, et al. Among authors: ratnayaka i. Genes Dev. 2022 Oct 1;36(19-20):1096. doi: 10.1101/gad.350249.122. Genes Dev. 2022. PMID: 36460466 Free PMC article. No abstract available.
Venous identity requires BMP signalling through ALK3.
Neal A, Nornes S, Payne S, Wallace MD, Fritzsche M, Louphrasitthiphol P, Wilkinson RN, Chouliaras KM, Liu K, Plant K, Sholapurkar R, Ratnayaka I, Herzog W, Bond G, Chico T, Bou-Gharios G, De Val S. Neal A, et al. Among authors: ratnayaka i. Nat Commun. 2019 Jan 28;10(1):453. doi: 10.1038/s41467-019-08315-w. Nat Commun. 2019. PMID: 30692543 Free PMC article.
PHD2 inactivation in Type I cells drives HIF-2α-dependent multilineage hyperplasia and the formation of paraganglioma-like carotid bodies.
Fielding JW, Hodson EJ, Cheng X, Ferguson DJP, Eckardt L, Adam J, Lip P, Maton-Howarth M, Ratnayaka I, Pugh CW, Buckler KJ, Ratcliffe PJ, Bishop T. Fielding JW, et al. Among authors: ratnayaka i. J Physiol. 2018 Jun 19;596(18):4393-412. doi: 10.1113/JP275996. Online ahead of print. J Physiol. 2018. PMID: 29917232 Free PMC article.
Correction: SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development. Development doi: 10.1242/dev.146241.
Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Fossat N, Radziewic T, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, Tam PPL, Carroll J, Dejana E, Schulte-Merker S, Hogan BM, Beltrame M, De Val S, Francois M. Chiang IK, et al. Among authors: ratnayaka i. Development. 2017 Oct 15;144(20):3847-3848. doi: 10.1242/dev.159715. Development. 2017. PMID: 29042478 Free PMC article. No abstract available.
SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development.
Chiang IK, Fritzsche M, Pichol-Thievend C, Neal A, Holmes K, Lagendijk A, Overman J, D'Angelo D, Omini A, Hermkens D, Lesieur E, Liu K, Ratnayaka I, Corada M, Bou-Gharios G, Carroll J, Dejana E, Schulte-Merker S, Hogan B, Beltrame M, De Val S, Francois M. Chiang IK, et al. Among authors: ratnayaka i. Development. 2017 Jul 15;144(14):2629-2639. doi: 10.1242/dev.146241. Epub 2017 Jun 15. Development. 2017. PMID: 28619820 Free PMC article.
MEF2 transcription factors are key regulators of sprouting angiogenesis.
Sacilotto N, Chouliaras KM, Nikitenko LL, Lu YW, Fritzsche M, Wallace MD, Nornes S, García-Moreno F, Payne S, Bridges E, Liu K, Biggs D, Ratnayaka I, Herbert SP, Molnár Z, Harris AL, Davies B, Bond GL, Bou-Gharios G, Schwarz JJ, De Val S. Sacilotto N, et al. Among authors: ratnayaka i. Genes Dev. 2016 Oct 15;30(20):2297-2309. doi: 10.1101/gad.290619.116. Genes Dev. 2016. PMID: 27898394 Free PMC article.
Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP.
Lu M, Breyssens H, Salter V, Zhong S, Hu Y, Baer C, Ratnayaka I, Sullivan A, Brown NR, Endicott J, Knapp S, Kessler BM, Middleton MR, Siebold C, Jones EY, Sviderskaya EV, Cebon J, John T, Caballero OL, Goding CR, Lu X. Lu M, et al. Among authors: ratnayaka i. Cancer Cell. 2016 Nov 14;30(5):822-823. doi: 10.1016/j.ccell.2016.09.019. Cancer Cell. 2016. PMID: 27846394 Free article. No abstract available.
32 results