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Selective modulation of the glucocorticoid receptor can distinguish between transrepression of NF-κB and AP-1.
De Bosscher K, Beck IM, Dejager L, Bougarne N, Gaigneaux A, Chateauvieux S, Ratman D, Bracke M, Tavernier J, Vanden Berghe W, Libert C, Diederich M, Haegeman G. De Bosscher K, et al. Among authors: ratman d. Cell Mol Life Sci. 2014 Jan;71(1):143-63. doi: 10.1007/s00018-013-1367-4. Epub 2013 Jun 20. Cell Mol Life Sci. 2014. PMID: 23784308 Free PMC article.
Coregulator profiling of the glucocorticoid receptor in lymphoid malignancies.
Clarisse D, Thommis J, Van Wesemael K, Houtman R, Ratman D, Tavernier J, Offner F, Beck I, De Bosscher K. Clarisse D, et al. Among authors: ratman d. Oncotarget. 2017 Nov 30;8(65):109675-109691. doi: 10.18632/oncotarget.22764. eCollection 2017 Dec 12. Oncotarget. 2017. PMID: 29312638 Free PMC article.
The autophagy receptor SQSTM1/p62 mediates anti-inflammatory actions of the selective NR3C1/glucocorticoid receptor modulator compound A (CpdA) in macrophages.
Mylka V, Deckers J, Ratman D, De Cauwer L, Thommis J, De Rycke R, Impens F, Libert C, Tavernier J, Vanden Berghe W, Gevaert K, De Bosscher K. Mylka V, et al. Among authors: ratman d. Autophagy. 2018;14(12):2049-2064. doi: 10.1080/15548627.2018.1495681. Epub 2018 Sep 14. Autophagy. 2018. PMID: 30215534 Free PMC article.
Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells.
Szarc vel Szic K, Op de Beeck K, Ratman D, Wouters A, Beck IM, Declerck K, Heyninck K, Fransen E, Bracke M, De Bosscher K, Lardon F, Van Camp G, Vanden Berghe W. Szarc vel Szic K, et al. Among authors: ratman d. PLoS One. 2014 Feb 3;9(2):e87850. doi: 10.1371/journal.pone.0087850. eCollection 2014. PLoS One. 2014. PMID: 24498382 Free PMC article.
Semi-synthetic sapogenin exerts neuroprotective effects by skewing the brain ischemia reperfusion transcriptome towards inflammatory resolution.
García-Pupo L, Sánchez JR, Ratman D, Pérez-Novo C, Declerck K, De Bosscher K, Markakis MN, Beemster G, Zaldo A, Nuñez Figueredo Y, Delgado-Hernández R, Vanden Berghe W. García-Pupo L, et al. Among authors: ratman d. Brain Behav Immun. 2017 Aug;64:103-115. doi: 10.1016/j.bbi.2017.04.002. Epub 2017 Apr 6. Brain Behav Immun. 2017. PMID: 28390980
16 results