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The Complex Integration of T-cell Metabolism and Immunotherapy.
Madden MZ, Rathmell JC. Madden MZ, et al. Among authors: rathmell jc. Cancer Discov. 2021 Jul;11(7):1636-1643. doi: 10.1158/2159-8290.CD-20-0569. Epub 2021 Apr 1. Cancer Discov. 2021. PMID: 33795235 Free PMC article. Review.
T cell metabolic fitness in antitumor immunity.
Siska PJ, Rathmell JC. Siska PJ, et al. Among authors: rathmell jc. Trends Immunol. 2015 Apr;36(4):257-64. doi: 10.1016/j.it.2015.02.007. Epub 2015 Mar 12. Trends Immunol. 2015. PMID: 25773310 Free PMC article. Review.
AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival.
Kishton RJ, Barnes CE, Nichols AG, Cohen S, Gerriets VA, Siska PJ, Macintyre AN, Goraksha-Hicks P, de Cubas AA, Liu T, Warmoes MO, Abel ED, Yeoh AE, Gershon TR, Rathmell WK, Richards KL, Locasale JW, Rathmell JC. Kishton RJ, et al. Among authors: rathmell jc, rathmell wk. Cell Metab. 2016 Apr 12;23(4):649-62. doi: 10.1016/j.cmet.2016.03.008. Cell Metab. 2016. PMID: 27076078 Free PMC article.
Nutrients and the microenvironment to feed a T cell army.
Johnson MO, Siska PJ, Contreras DC, Rathmell JC. Johnson MO, et al. Among authors: rathmell jc. Semin Immunol. 2016 Oct;28(5):505-513. doi: 10.1016/j.smim.2016.09.003. Epub 2016 Oct 3. Semin Immunol. 2016. PMID: 27712958 Free PMC article. Review.
Dysfunctional T cell metabolism in the tumor microenvironment.
Beckermann KE, Dudzinski SO, Rathmell JC. Beckermann KE, et al. Among authors: rathmell jc. Cytokine Growth Factor Rev. 2017 Jun;35:7-14. doi: 10.1016/j.cytogfr.2017.04.003. Epub 2017 Apr 23. Cytokine Growth Factor Rev. 2017. PMID: 28456467 Free PMC article. Review.
Metabolic Barriers to T Cell Function in Tumors.
Sugiura A, Rathmell JC. Sugiura A, et al. Among authors: rathmell jc. J Immunol. 2018 Jan 15;200(2):400-407. doi: 10.4049/jimmunol.1701041. J Immunol. 2018. PMID: 29311381 Free PMC article. Review.
Targeting PIM Kinase with PD1 Inhibition Improves Immunotherapeutic Antitumor T-cell Response.
Chatterjee S, Chakraborty P, Daenthanasanmak A, Iamsawat S, Andrejeva G, Luevano LA, Wolf M, Baliga U, Krieg C, Beeson CC, Mehrotra M, Hill EG, Rathmell JC, Yu XZ, Kraft AS, Mehrotra S. Chatterjee S, et al. Among authors: rathmell jc. Clin Cancer Res. 2019 Feb 1;25(3):1036-1049. doi: 10.1158/1078-0432.CCR-18-0706. Epub 2018 Oct 16. Clin Cancer Res. 2019. PMID: 30327305 Free PMC article.
Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.
Johnson MO, Wolf MM, Madden MZ, Andrejeva G, Sugiura A, Contreras DC, Maseda D, Liberti MV, Paz K, Kishton RJ, Johnson ME, de Cubas AA, Wu P, Li G, Zhang Y, Newcomb DC, Wells AD, Restifo NP, Rathmell WK, Locasale JW, Davila ML, Blazar BR, Rathmell JC. Johnson MO, et al. Among authors: rathmell jc, rathmell wk. Cell. 2018 Dec 13;175(7):1780-1795.e19. doi: 10.1016/j.cell.2018.10.001. Epub 2018 Nov 1. Cell. 2018. PMID: 30392958 Free PMC article.
224 results