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Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models.
Schulte ML, Fu A, Zhao P, Li J, Geng L, Smith ST, Kondo J, Coffey RJ, Johnson MO, Rathmell JC, Sharick JT, Skala MC, Smith JA, Berlin J, Washington MK, Nickels ML, Manning HC. Schulte ML, et al. Among authors: rathmell jc. Nat Med. 2018 Feb;24(2):194-202. doi: 10.1038/nm.4464. Epub 2018 Jan 15. Nat Med. 2018. PMID: 29334372 Free PMC article.
AIF Is "Always In Fashion" for T Cells.
Johnson MO, Rathmell JC. Johnson MO, et al. Among authors: rathmell jc. Immunity. 2016 Jan 19;44(1):11-13. doi: 10.1016/j.immuni.2015.12.015. Immunity. 2016. PMID: 26789917 Free PMC article.
A guide to immunometabolism for immunologists.
O'Neill LA, Kishton RJ, Rathmell J. O'Neill LA, et al. Nat Rev Immunol. 2016 Sep;16(9):553-65. doi: 10.1038/nri.2016.70. Epub 2016 Jul 11. Nat Rev Immunol. 2016. PMID: 27396447 Free PMC article. Review.
Nutrients and the microenvironment to feed a T cell army.
Johnson MO, Siska PJ, Contreras DC, Rathmell JC. Johnson MO, et al. Among authors: rathmell jc. Semin Immunol. 2016 Oct;28(5):505-513. doi: 10.1016/j.smim.2016.09.003. Epub 2016 Oct 3. Semin Immunol. 2016. PMID: 27712958 Free PMC article. Review.
A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product.
Liberti MV, Dai Z, Wardell SE, Baccile JA, Liu X, Gao X, Baldi R, Mehrmohamadi M, Johnson MO, Madhukar NS, Shestov AA, Chio IIC, Elemento O, Rathmell JC, Schroeder FC, McDonnell DP, Locasale JW. Liberti MV, et al. Among authors: rathmell jc. Cell Metab. 2017 Oct 3;26(4):648-659.e8. doi: 10.1016/j.cmet.2017.08.017. Epub 2017 Sep 14. Cell Metab. 2017. PMID: 28918937 Free PMC article.
Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells.
Zhang Q, Jeppesen DK, Higginbotham JN, Demory Beckler M, Poulin EJ, Walsh AJ, Skala MC, McKinley ET, Manning HC, Hight MR, Schulte ML, Watt KR, Ayers GD, Wolf MM, Andrejeva G, Rathmell JC, Franklin JL, Coffey RJ. Zhang Q, et al. Among authors: rathmell jc. Cell Mol Gastroenterol Hepatol. 2018 Jan 31;5(4):627-629.e6. doi: 10.1016/j.jcmgh.2018.01.013. eCollection 2018. Cell Mol Gastroenterol Hepatol. 2018. PMID: 29930982 Free PMC article. No abstract available.
224 results