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The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation.
Flegel J, Shaaban S, Jia ZJ, Schulte B, Lian Y, Krzyzanowski A, Metz M, Schneidewind T, Wesseler F, Flegel A, Reich A, Brause A, Xue G, Zhang M, Dötsch L, Stender ID, Hoffmann JE, Scheel R, Janning P, Rastinejad F, Schade D, Strohmann C, Antonchick AP, Sievers S, Moura-Alves P, Ziegler S, Waldmann H. Flegel J, et al. Among authors: rastinejad f. J Med Chem. 2022 Dec 22;65(24):16268-16289. doi: 10.1021/acs.jmedchem.2c00956. Epub 2022 Dec 2. J Med Chem. 2022. PMID: 36459434 Free PMC article.
The protein architecture and allosteric landscape of HNF4α.
Rastinejad F. Rastinejad F. Front Endocrinol (Lausanne). 2023 Sep 4;14:1219092. doi: 10.3389/fendo.2023.1219092. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37732120 Free PMC article. Review.
Decoding Allosteric Control in Hypoxia-Inducible Factors.
Zhuang J, Shang Q, Rastinejad F, Wu D. Zhuang J, et al. Among authors: rastinejad f. J Mol Biol. 2024 Feb 1;436(3):168352. doi: 10.1016/j.jmb.2023.168352. Epub 2023 Nov 5. J Mol Biol. 2024. PMID: 37935255 Review.
Monoterpenoid aryl hydrocarbon receptor allosteric antagonists protect against ultraviolet skin damage in female mice.
Ondrová K, Zůvalová I, Vyhlídalová B, Krasulová K, Miková E, Vrzal R, Nádvorník P, Nepal B, Kortagere S, Kopečná M, Kopečný D, Šebela M, Rastinejad F, Pu H, Soural M, Rolfes KM, Haarmann-Stemmann T, Li H, Mani S, Dvořák Z. Ondrová K, et al. Among authors: rastinejad f. Nat Commun. 2023 May 11;14(1):2728. doi: 10.1038/s41467-023-38478-6. Nat Commun. 2023. PMID: 37169746 Free PMC article.
Identification of oleoylethanolamide as an endogenous ligand for HIF-3α.
Diao X, Ye F, Zhang M, Ren X, Tian X, Lu J, Sun X, Hou Z, Chen X, Li F, Zhuang J, Ding H, Peng C, Rastinejad F, Luo C, Wu D. Diao X, et al. Among authors: rastinejad f. Nat Commun. 2022 May 9;13(1):2529. doi: 10.1038/s41467-022-30338-z. Nat Commun. 2022. PMID: 35534502 Free PMC article.
Human gut bacteria produce ΤΗ17-modulating bile acid metabolites.
Paik D, Yao L, Zhang Y, Bae S, D'Agostino GD, Zhang M, Kim E, Franzosa EA, Avila-Pacheco J, Bisanz JE, Rakowski CK, Vlamakis H, Xavier RJ, Turnbaugh PJ, Longman RS, Krout MR, Clish CB, Rastinejad F, Huttenhower C, Huh JR, Devlin AS. Paik D, et al. Among authors: rastinejad f. Nature. 2022 Mar;603(7903):907-912. doi: 10.1038/s41586-022-04480-z. Epub 2022 Mar 16. Nature. 2022. PMID: 35296854 Free PMC article.
DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumor immunotolerance.
D'Anna F, Van Dyck L, Xiong J, Zhao H, Berrens RV, Qian J, Bieniasz-Krzywiec P, Chandra V, Schoonjans L, Matthews J, De Smedt J, Minnoye L, Amorim R, Khorasanizadeh S, Yu Q, Zhao L, De Borre M, Savvides SN, Simon MC, Carmeliet P, Reik W, Rastinejad F, Mazzone M, Thienpont B, Lambrechts D. D'Anna F, et al. Among authors: rastinejad f. Genome Biol. 2020 Jul 27;21(1):182. doi: 10.1186/s13059-020-02087-z. Genome Biol. 2020. PMID: 32718321 Free PMC article.
87 results