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The 1,2,3-triazole ring as a bioisostere in medicinal chemistry.
Bonandi E, Christodoulou MS, Fumagalli G, Perdicchia D, Rastelli G, Passarella D. Bonandi E, et al. Among authors: rastelli g. Drug Discov Today. 2017 Oct;22(10):1572-1581. doi: 10.1016/j.drudis.2017.05.014. Epub 2017 Jul 1. Drug Discov Today. 2017. PMID: 28676407 Review.
Probing an Allosteric Pocket of CDK2 with Small Molecules.
Christodoulou MS, Caporuscio F, Restelli V, Carlino L, Cannazza G, Costanzi E, Citti C, Lo Presti L, Pisani P, Battistutta R, Broggini M, Passarella D, Rastelli G. Christodoulou MS, et al. Among authors: rastelli g. ChemMedChem. 2017 Jan 5;12(1):33-41. doi: 10.1002/cmdc.201600474. Epub 2016 Dec 19. ChemMedChem. 2017. PMID: 27860401
Structure-Activity Relationships of Hexahydrocyclopenta[c]quinoline Derivatives as Allosteric Inhibitors of CDK2 and EGFR.
Carlino L, Christodoulou MS, Restelli V, Caporuscio F, Foschi F, Semrau MS, Costanzi E, Tinivella A, Pinzi L, Lo Presti L, Battistutta R, Storici P, Broggini M, Passarella D, Rastelli G. Carlino L, et al. Among authors: rastelli g. ChemMedChem. 2018 Dec 20;13(24):2627-2634. doi: 10.1002/cmdc.201800687. Epub 2018 Nov 20. ChemMedChem. 2018. PMID: 30457710 Free article.
Promising Non-cytotoxic Monosubstituted Chalcones to Target Monoamine Oxidase-B.
Iacovino LG, Pinzi L, Facchetti G, Bortolini B, Christodoulou MS, Binda C, Rastelli G, Rimoldi I, Passarella D, Di Paolo ML, Dalla Via L. Iacovino LG, et al. Among authors: rastelli g. ACS Med Chem Lett. 2021 Jun 14;12(7):1151-1158. doi: 10.1021/acsmedchemlett.1c00238. eCollection 2021 Jul 8. ACS Med Chem Lett. 2021. PMID: 34262643 Free PMC article.
211 results