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SIK2 inhibition enhances PARP inhibitor activity synergistically in ovarian and triple-negative breast cancers.
J Clin Invest. 2022 Jun 1;132(11):e146471. doi: 10.1172/JCI146471.
J Clin Invest. 2022.
PMID: 35642638
Free PMC article.
Poly(adenosine diphosphate ribose) polymerase inhibitors induce autophagy-mediated drug resistance in ovarian cancer cells, xenografts, and patient-derived xenograft models.
Santiago-O'Farrill JM, Weroha SJ, Hou X, Oberg AL, Heinzen EP, Maurer MJ, Pang L, Rask P, Amaravadi RK, Becker SE, Romero I, Rubio MJ, Matias-Guiu X, Santacana M, Llombart-Cussac A, Poveda A, Lu Z, Bast RC Jr.
Santiago-O'Farrill JM, et al.
Cancer. 2020 Feb 15;126(4):894-907. doi: 10.1002/cncr.32600. Epub 2019 Nov 12.
Cancer. 2020.
PMID: 31714594
Free PMC article.
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Elimination of dormant, autophagic ovarian cancer cells and xenografts through enhanced sensitivity to anaplastic lymphoma kinase inhibition.
Blessing AM, Santiago-O'Farrill JM, Mao W, Pang L, Ning J, Pak D, Bollu LR, Rask P, Iles L, Yang H, Tran S, Elmir E, Bartholomeusz G, Langley R, Lu Z, Bast RC Jr.
Blessing AM, et al.
Cancer. 2020 Aug 1;126(15):3579-3592. doi: 10.1002/cncr.32985. Epub 2020 Jun 2.
Cancer. 2020.
PMID: 32484926
Free PMC article.
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A Novel Salt Inducible Kinase 2 Inhibitor, ARN-3261, Sensitizes Ovarian Cancer Cell Lines and Xenografts to Carboplatin.
Fan D, Yang H, Mao W, Rask PJ, Pang L, Xu C, Vankayalapat H, Ahmed AA, Bast RC Jr, Lu Z.
Fan D, et al. Among authors: rask pj.
Cancers (Basel). 2021 Jan 25;13(3):446. doi: 10.3390/cancers13030446.
Cancers (Basel). 2021.
PMID: 33503955
Free PMC article.
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Directed evolution of cyclic peptides for inhibition of autophagy.
Gray JP, Uddin MN, Chaudhari R, Sutton MN, Yang H, Rask P, Locke H, Engel BJ, Batistatou N, Wang J, Grindel BJ, Bhattacharya P, Gammon ST, Zhang S, Piwnica-Worms D, Kritzer JA, Lu Z, Bast RC Jr, Millward SW.
Gray JP, et al.
Chem Sci. 2021 Jan 13;12(10):3526-3543. doi: 10.1039/d0sc03603j.
Chem Sci. 2021.
PMID: 34163626
Free PMC article.
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DIRAS3-Derived Peptide Inhibits Autophagy in Ovarian Cancer Cells by Binding to Beclin1.
Sutton MN, Huang GY, Liang X, Sharma R, Reger AS, Mao W, Pang L, Rask PJ, Lee K, Gray JP, Hurwitz AM, Palzkill T, Millward SW, Kim C, Lu Z, Bast RC Jr.
Sutton MN, et al. Among authors: rask pj.
Cancers (Basel). 2019 Apr 18;11(4):557. doi: 10.3390/cancers11040557.
Cancers (Basel). 2019.
PMID: 31003488
Free PMC article.
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Long non-coding RNAs differential expression in breast cancer subtypes: What do we know?
Mathias C, Zambalde EP, Rask P, Gradia DF, de Oliveira JC.
Mathias C, et al.
Clin Genet. 2019 May;95(5):558-568. doi: 10.1111/cge.13502. Epub 2019 Jan 22.
Clin Genet. 2019.
PMID: 30614523
Review.
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