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Page 1
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7.
Gütschow M, Eynde JJV, Jampilek J, Kang C, Mangoni AA, Fossa P, Karaman R, Trabocchi A, Scott PJH, Reynisson J, Rapposelli S, Galdiero S, Winum JY, Brullo C, Prokai-Tatrai K, Sharma AK, Schapira M, Azuma YT, Cerchia L, Spetea M, Torri G, Collina S, Geronikaki A, García-Sosa AT, Vasconcelos MH, Sousa ME, Kosalec I, Tuccinardi T, Duarte IF, Salvador JAR, Bertinaria M, Pellecchia M, Amato J, Rastelli G, Gomes PAC, Guedes RC, Sabatier JM, Estévez-Braun A, Pagano B, Mangani S, Ragno R, Kokotos G, Brindisi M, González FV, Borges F, Miloso M, Rautio J, Muñoz-Torrero D. Gütschow M, et al. Among authors: rapposelli s. Molecules. 2020 Jun 28;25(13):2968. doi: 10.3390/molecules25132968. Molecules. 2020. PMID: 32605268 Free PMC article.
Hit-to-Lead Optimization of Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists with a Diphenylmethane-Scaffold: Design, Synthesis, and Biological Study.
Chiellini G, Nesi G, Sestito S, Chiarugi S, Runfola M, Espinoza S, Sabatini M, Bellusci L, Laurino A, Cichero E, Gainetdinov RR, Fossa P, Raimondi L, Zucchi R, Rapposelli S. Chiellini G, et al. Among authors: rapposelli s. J Med Chem. 2016 Nov 10;59(21):9825-9836. doi: 10.1021/acs.jmedchem.6b01092. Epub 2016 Oct 21. J Med Chem. 2016. PMID: 27731647
Endogenous 3-Iodothyronamine (T1AM) and Synthetic Thyronamine-like Analog SG-2 Act as Novel Pleiotropic Neuroprotective Agents Through the Modulation of SIRT6.
Bellusci L, Runfola M, Carnicelli V, Sestito S, Fulceri F, Santucci F, Lenzi P, Fornai F, Rapposelli S, Origlia N, Zucchi R, Chiellini G. Bellusci L, et al. Among authors: rapposelli s. Molecules. 2020 Feb 26;25(5):1054. doi: 10.3390/molecules25051054. Molecules. 2020. PMID: 32110992 Free PMC article.
NO-releasing hybrids of cardiovascular drugs.
Martelli A, Rapposelli S, Calderone V. Martelli A, et al. Among authors: rapposelli s. Curr Med Chem. 2006;13(6):609-25. doi: 10.2174/092986706776055634. Curr Med Chem. 2006. PMID: 16529554 Review.
Synthesis of stable analogues of geranylgeranyl diphosphate possessing a (Z,E,E)-geranylgeranyl side chain, docking analysis, and biological assays for prenyl protein transferase inhibition.
Minutolo F, Bertini S, Betti L, Danesi R, Gervasi G, Giannaccini G, Martinelli A, Papini AM, Peroni E, Placanica G, Rapposelli S, Tuccinardi T, Macchia M. Minutolo F, et al. Among authors: rapposelli s. ChemMedChem. 2006 Feb;1(2):218-24. doi: 10.1002/cmdc.200500010. ChemMedChem. 2006. PMID: 16892354
Monoaryl-substituted salicylaldoximes as ligands for estrogen receptor beta.
Minutolo F, Bellini R, Bertini S, Carboni I, Lapucci A, Pistolesi L, Prota G, Rapposelli S, Solati F, Tuccinardi T, Martinelli A, Stossi F, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA, Macchia M. Minutolo F, et al. Among authors: rapposelli s. J Med Chem. 2008 Mar 13;51(5):1344-51. doi: 10.1021/jm701396g. Epub 2008 Feb 13. J Med Chem. 2008. PMID: 18269232
119 results