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JNK pathway and heat shock response mediate the survival of C26 colon carcinoma bearing mice fed with the mushroom Pleurotus eryngii var. eryngii without affecting tumor growth or cachexia.
Barone R , Caruso Bavisotto C , Rappa F , Gargano ML , Macaluso F , Paladino L , Vitale AM , Alfano S , Campanella C , Gorska M , Di Felice V , Cappello F , Venturella G , Marino Gammazza A . Barone R , et al. Among authors: rappa f. Food Funct. 2021 Apr 7;12(7):3083-3095. doi: 10.1039/d0fo03171b. Epub 2021 Mar 15. Food Funct. 2021. PMID: 33720221
Changes in immunohistochemical levels and subcellular localization after therapy and correlation and colocalization with CD68 suggest a pathogenetic role of Hsp60 in ulcerative colitis.
Tomasello G, Rodolico V, Zerilli M, Martorana A, Bucchieri F, Pitruzzella A, Marino Gammazza A, David S, Rappa F, Zummo G, Damiani P, Accomando S, Rizzo M, de Macario EC, Macario AJ, Cappello F. Tomasello G, et al. Among authors: rappa f. Appl Immunohistochem Mol Morphol. 2011 Dec;19(6):552-61. doi: 10.1097/PAI.0b013e3182118e5f. Appl Immunohistochem Mol Morphol. 2011. PMID: 21441812 Clinical Trial.
Heat-shock protein 60 kDa and atherogenic dyslipidemia in patients with untreated mild periodontitis: a pilot study.
Rizzo M, Cappello F, Marfil R, Nibali L, Marino Gammazza A, Rappa F, Bonaventura G, Galindo-Moreno P, O'Valle F, Zummo G, Conway de Macario E, Macario AJ, Mesa F. Rizzo M, et al. Among authors: rappa f. Cell Stress Chaperones. 2012 May;17(3):399-407. doi: 10.1007/s12192-011-0315-1. Epub 2012 Jan 4. Cell Stress Chaperones. 2012. PMID: 22215516 Free PMC article.
Silk fibroin scaffolds enhance cell commitment of adult rat cardiac progenitor cells.
Di Felice V, Serradifalco C, Rizzuto L, De Luca A, Rappa F, Barone R, Di Marco P, Cassata G, Puleio R, Verin L, Motta A, Migliaresi C, Guercio A, Zummo G. Di Felice V, et al. Among authors: rappa f. J Tissue Eng Regen Med. 2015 Nov;9(11):E51-64. doi: 10.1002/term.1739. Epub 2013 Apr 17. J Tissue Eng Regen Med. 2015. PMID: 23592297
Gut microbiota imbalance and chaperoning system malfunction are central to ulcerative colitis pathogenesis and can be counteracted with specifically designed probiotics: a working hypothesis.
Bellavia M, Tomasello G, Romeo M, Damiani P, Lo Monte AI, Lozio L, Campanella C, Marino Gammazza A, Rappa F, Zummo G, Cocchi M, Conway de Macario E, Macario AJ, Cappello F. Bellavia M, et al. Among authors: rappa f. Med Microbiol Immunol. 2013 Dec;202(6):393-406. doi: 10.1007/s00430-013-0305-2. Epub 2013 Jul 18. Med Microbiol Immunol. 2013. PMID: 23864544 Review.
Elevated blood Hsp60, its structural similarities and cross-reactivity with thyroid molecules, and its presence on the plasma membrane of oncocytes point to the chaperonin as an immunopathogenic factor in Hashimoto's thyroiditis.
Marino Gammazza A, Rizzo M, Citarrella R, Rappa F, Campanella C, Bucchieri F, Patti A, Nikolic D, Cabibi D, Amico G, Conaldi PG, San Biagio PL, Montalto G, Farina F, Zummo G, Conway de Macario E, Macario AJ, Cappello F. Marino Gammazza A, et al. Among authors: rappa f. Cell Stress Chaperones. 2014 May;19(3):343-53. doi: 10.1007/s12192-013-0460-9. Epub 2013 Sep 22. Cell Stress Chaperones. 2014. PMID: 24057177 Free PMC article.
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