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Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis.
Canales-Herrerias P, Uzzan M, Seki A, Czepielewski RS, Verstockt B, Livanos AE, Raso F, Dunn A, Dai D, Wang A, Al-Taie Z, Martin J, Laurent T, Ko HM, Tokuyama M, Tankelevich M, Meringer H, Cossarini F, Jha D, Krek A, Paulsen JD, Taylor MD, Nakadar MZ, Wong J, Erlich EC, Mintz RL, Onufer EJ, Helmink BA, Sharma K, Rosenstein A, Ganjian D, Chung G, Dawson T, Juarez J, Yajnik V, Cerutti A, Faith JJ, Suarez-Farinas M, Argmann C, Petralia F, Randolph GJ, Polydorides AD, Reboldi A, Colombel JF, Mehandru S. Canales-Herrerias P, et al. Among authors: randolph gj. Sci Immunol. 2024 Apr 19;9(94):eadg7549. doi: 10.1126/sciimmunol.adg7549. Epub 2024 Apr 19. Sci Immunol. 2024. PMID: 38640252
Human serous cavity macrophages and dendritic cells possess counterparts in the mouse with a distinct distribution between species.
Han J, Gallerand A, Erlich EC, Helmink BA, Mair I, Li X, Eckhouse SR, Dimou FM, Shakhsheer BA, Phelps HM, Chan MM, Mintz RL, Lee DD, Schilling JD, Finlay CM, Allen JE, Jakubzick CV, Else KJ, Onufer EJ, Zhang N, Randolph GJ. Han J, et al. Among authors: randolph gj. Nat Immunol. 2024 Jan;25(1):155-165. doi: 10.1038/s41590-023-01688-7. Epub 2023 Dec 15. Nat Immunol. 2024. PMID: 38102487
Staphylococcus aureus α-toxin impairs early neutrophil localization via electrogenic disruption of store-operated calcium entry.
Yang F, Suo M, Weli H, Wong M, Junidi A, Cummings C, Johnson R, Mallory K, Liu AY, Greenberg ZJ, Schuettpelz LG, Miller MJ, Luke CJ, Randolph GJ, Zinselmeyer BH, Wardenburg JB, Clemens RA. Yang F, et al. Among authors: randolph gj. Cell Rep. 2023 Nov 28;42(11):113394. doi: 10.1016/j.celrep.2023.113394. Epub 2023 Nov 10. Cell Rep. 2023. PMID: 37950870 Free PMC article.
Fibrosis induced by resident macrophages has divergent roles in pancreas inflammatory injury and PDAC.
Baer JM, Zuo C, Kang LI, de la Lastra AA, Borcherding NC, Knolhoff BL, Bogner SJ, Zhu Y, Yang L, Laurent J, Lewis MA, Zhang N, Kim KW, Fields RC, Yokoyama WM, Mills JC, Ding L, Randolph GJ, DeNardo DG. Baer JM, et al. Among authors: randolph gj. Nat Immunol. 2023 Sep;24(9):1443-1457. doi: 10.1038/s41590-023-01579-x. Epub 2023 Aug 10. Nat Immunol. 2023. PMID: 37563309 Free PMC article.
Defects in vein valve PROX1/FOXC2 antithrombotic pathway in endothelial cells drive the hypercoagulable state induced by trauma and critical illness.
Hoofnagle MH, Hess A, Nalugo M, Ghosh S, Hughes SW, Fuchs A, Welsh JD, Kahn ML, Bochicchio GV, Randolph GJ, Leonard JM, Turnbull IR. Hoofnagle MH, et al. Among authors: randolph gj. J Trauma Acute Care Surg. 2023 Aug 1;95(2):197-204. doi: 10.1097/TA.0000000000003945. Epub 2023 Apr 19. J Trauma Acute Care Surg. 2023. PMID: 37072887
T helper 2 cells control monocyte to tissue-resident macrophage differentiation during nematode infection of the pleural cavity.
Finlay CM, Parkinson JE, Zhang L, Chan BHK, Ajendra J, Chenery A, Morrison A, Kaymak I, Houlder EL, Murtuza Baker S, Dickie BR, Boon L, Konkel JE, Hepworth MR, MacDonald AS, Randolph GJ, Rückerl D, Allen JE. Finlay CM, et al. Among authors: randolph gj. Immunity. 2023 May 9;56(5):1064-1081.e10. doi: 10.1016/j.immuni.2023.02.016. Epub 2023 Mar 21. Immunity. 2023. PMID: 36948193 Free article.
221 results