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2011 1
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Integrating artificial intelligence-based epitope prediction in a SARS-CoV-2 antibody discovery pipeline: caution is warranted.
Acar DD, Witkowski W, Wejda M, Wei R, Desmet T, Schepens B, De Cae S, Sedeyn K, Eeckhaut H, Fijalkowska D, Roose K, Vanmarcke S, Poupon A, Jochmans D, Zhang X, Abdelnabi R, Foo CS, Weynand B, Reiter D, Callewaert N, Remaut H, Neyts J, Saelens X, Gerlo S, Vandekerckhove L. Acar DD, et al. Among authors: abdelnabi r. EBioMedicine. 2024 Feb;100:104960. doi: 10.1016/j.ebiom.2023.104960. Epub 2024 Jan 16. EBioMedicine. 2024. PMID: 38232633 Free PMC article.
Design, synthesis, and lead optimization of piperazinyl-pyrimidine analogues as potent small molecules targeting the viral capping machinery of Chikungunya virus.
Battisti V, Moesslacher J, Abdelnabi R, Leyssen P, Rosales Rosas AL, Langendries L, Aufy M, Studenik C, Kratz JM, Rollinger JM, Puerstinger G, Neyts J, Delang L, Urban E, Langer T. Battisti V, et al. Among authors: abdelnabi r. Eur J Med Chem. 2024 Jan 15;264:116010. doi: 10.1016/j.ejmech.2023.116010. Epub 2023 Dec 8. Eur J Med Chem. 2024. PMID: 38104375 Free article.
Optimized vaccine candidate MVA-S(3P) fully protects against SARS-CoV-2 infection in hamsters.
Abdelnabi R, Pérez P, Astorgano D, Albericio G, Kerstens W, Thibaut HJ, Coelmont L, Weynand B, Labiod N, Delgado R, Montenegro D, Puentes E, Rodríguez E, Neyts J, Dallmeier K, Esteban M, García-Arriaza J. Abdelnabi R, et al. Front Immunol. 2023 Oct 18;14:1163159. doi: 10.3389/fimmu.2023.1163159. eCollection 2023. Front Immunol. 2023. PMID: 37920464 Free PMC article.
Broadly potent anti-SARS-CoV-2 antibody shares 93% of epitope with ACE2 and provides full protection in monkeys.
Fenwick C, Turelli P, Duhoo Y, Lau K, Herate C, Marlin R, Lamrayah M, Campos J, Esteves-Leuenberger L, Farina A, Raclot C, Genet V, Fiscalini F, Cesborn J, Perez L, Dereuddre-Bosquet N, Contreras V, Lheureux K, Relouzat F, Abdelnabi R, Leyssen P, Lévy Y, Pojer F, Le Grand R, Trono D, Pantaleo G. Fenwick C, et al. Among authors: abdelnabi r. J Infect. 2023 Dec;87(6):524-537. doi: 10.1016/j.jinf.2023.10.008. Epub 2023 Oct 16. J Infect. 2023. PMID: 37852477 Free article.
68 results