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Multi-site investigation of strategies for the clinical implementation of CYP2D6 genotyping to guide drug prescribing.
Cavallari LH, Van Driest SL, Prows CA, Bishop JR, Limdi NA, Pratt VM, Ramsey LB, Smith DM, Tuteja S, Duong BQ, Hicks JK, Lee JC, Obeng AO, Beitelshees AL, Bell GC, Blake K, Crona DJ, Dressler L, Gregg RA, Hines LJ, Scott SA, Shelton RC, Weitzel KW, Johnson JA, Peterson JF, Empey PE, Skaar TC; IGNITE Network. Cavallari LH, et al. Among authors: ramsey lb. Genet Med. 2019 Oct;21(10):2255-2263. doi: 10.1038/s41436-019-0484-3. Epub 2019 Mar 21. Genet Med. 2019. PMID: 30894703 Free PMC article.
Concordance of DMET plus genotyping results with those of orthogonal genotyping methods.
Fernandez CA, Smith C, Yang W, Lorier R, Crews KR, Kornegay N, Hicks JK, Stewart CF, Kawedia JD, Ramsey LB, Liu C, Evans WE, Relling MV, Broeckel U. Fernandez CA, et al. Among authors: ramsey lb. Clin Pharmacol Ther. 2012 Sep;92(3):360-5. doi: 10.1038/clpt.2012.95. Epub 2012 Aug 8. Clin Pharmacol Ther. 2012. PMID: 22871999 Free PMC article.
NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells.
Paugh SW, Bonten EJ, Savic D, Ramsey LB, Thierfelder WE, Gurung P, Malireddi RK, Actis M, Mayasundari A, Min J, Coss DR, Laudermilk LT, Panetta JC, McCorkle JR, Fan Y, Crews KR, Stocco G, Wilkinson MR, Ferreira AM, Cheng C, Yang W, Karol SE, Fernandez CA, Diouf B, Smith C, Hicks JK, Zanut A, Giordanengo A, Crona D, Bianchi JJ, Holmfeldt L, Mullighan CG, den Boer ML, Pieters R, Jeha S, Dunwell TL, Latif F, Bhojwani D, Carroll WL, Pui CH, Myers RM, Guy RK, Kanneganti TD, Relling MV, Evans WE. Paugh SW, et al. Among authors: ramsey lb. Nat Genet. 2015 Jun;47(6):607-14. doi: 10.1038/ng.3283. Epub 2015 May 4. Nat Genet. 2015. PMID: 25938942 Free PMC article.
Gene-Based Dose Optimization in Children.
Ramsey LB, Brown JT, Vear SI, Bishop JR, Van Driest SL. Ramsey LB, et al. Annu Rev Pharmacol Toxicol. 2020 Jan 6;60:311-331. doi: 10.1146/annurev-pharmtox-010919-023459. Epub 2019 Jul 5. Annu Rev Pharmacol Toxicol. 2020. PMID: 31283429 Free PMC article. Review.
107 results