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Evaluating the oral delivery of GalNAc-conjugated siRNAs in rodents and non-human primates.
Yu M, Qin J, Liu X, Ramsden D, Williams B, Zlatev I, Guenther D, Matsuda S, Tymon R, Darcy J, Wong C, Tsung J, Zawaneh P, Chong S, Theile CS, Taneja N, Rogers A, Liu J, Castellanos-Rizaldos E, Bond S, So K, Denoncourt J, Castoreno A, Manoharan M, Wu JT, Fitzgerald K, Maier MA, Jadhav V, Nair JK. Yu M, et al. Among authors: ramsden d. Nucleic Acids Res. 2024 May 14:gkae350. doi: 10.1093/nar/gkae350. Online ahead of print. Nucleic Acids Res. 2024. PMID: 38742636
Quantitative evaluation of trastuzumab deruxtecan pharmacokinetics and pharmacodynamics in mouse models of varying degrees of HER2 expression.
Vasalou C, Proia TA, Kazlauskas L, Przybyla A, Sung M, Mamidi S, Maratea K, Griffin M, Sargeant R, Urosevic J, Rosenbaum AI, Yuan J, Aluri KC, Ramsden D, Hariparsad N, Jones RDO, Mettetal JT. Vasalou C, et al. Among authors: ramsden d. CPT Pharmacometrics Syst Pharmacol. 2024 Mar 26. doi: 10.1002/psp4.13133. Online ahead of print. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38532525 Free article.
Stepwise requirements for polymerases δ and θ in theta-mediated end joining.
Stroik S, Carvajal-Garcia J, Gupta D, Edwards A, Luthman A, Wyatt DW, Dannenberg RL, Feng W, Kunkel TA, Gupta GP, Hedglin M, Wood R, Doublié S, Rothenberg E, Ramsden DA. Stroik S, et al. Among authors: ramsden da. Nature. 2023 Nov;623(7988):836-841. doi: 10.1038/s41586-023-06729-7. Epub 2023 Nov 15. Nature. 2023. PMID: 37968395
Considerations from an International Regulatory and Pharmaceutical Industry (IQ MPS Affiliate) Workshop on the Standardization of Complex In Vitro Models in Drug Development.
Tomlinson L, Ramsden D, Leite SB, Beken S, Bonzo JA, Brown P, Candarlioglu PL, Chan TS, Chen E, Choi CK, David R, Delrue N, Devine PJ, Ford K, Garcia MI, Gosset JR, Hewitt P, Homan K, Irrechukwu O, Kopec AK, Liras JL, Mandlekar S, Raczynski A, Sadrieh N, Sakatis MZ, Siegel J, Sung K, Sunyovszki I, Van Vleet TR, Ekert JE, Hardwick RN. Tomlinson L, et al. Among authors: ramsden d. Adv Biol (Weinh). 2023 Oct 9:e2300131. doi: 10.1002/adbi.202300131. Online ahead of print. Adv Biol (Weinh). 2023. PMID: 37814378
Drug transporters in drug disposition - the year 2022 in review.
Chothe PP, Mitra P, Nakakariya M, Ramsden D, Rotter CJ, Sandoval P, Tohyama K. Chothe PP, et al. Among authors: ramsden d. Drug Metab Rev. 2023 Nov;55(4):343-370. doi: 10.1080/03602532.2023.2252618. Epub 2023 Sep 6. Drug Metab Rev. 2023. PMID: 37644867 Review.
360 results