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Tumor immune evasion arises through loss of TNF sensitivity.
Kearney CJ, Vervoort SJ, Hogg SJ, Ramsbottom KM, Freeman AJ, Lalaoui N, Pijpers L, Michie J, Brown KK, Knight DA, Sutton V, Beavis PA, Voskoboinik I, Darcy PK, Silke J, Trapani JA, Johnstone RW, Oliaro J. Kearney CJ, et al. Among authors: ramsbottom km. Sci Immunol. 2018 May 18;3(23):eaar3451. doi: 10.1126/sciimmunol.aar3451. Sci Immunol. 2018. PMID: 29776993
Antagonism of IAPs Enhances CAR T-cell Efficacy.
Michie J, Beavis PA, Freeman AJ, Vervoort SJ, Ramsbottom KM, Narasimhan V, Lelliott EJ, Lalaoui N, Ramsay RG, Johnstone RW, Silke J, Darcy PK, Voskoboinik I, Kearney CJ, Oliaro J. Michie J, et al. Among authors: ramsbottom km. Cancer Immunol Res. 2019 Feb;7(2):183-192. doi: 10.1158/2326-6066.CIR-18-0428. Epub 2019 Jan 16. Cancer Immunol Res. 2019. PMID: 30651288
Natural Killer Cells Suppress T Cell-Associated Tumor Immune Evasion.
Freeman AJ, Vervoort SJ, Ramsbottom KM, Kelly MJ, Michie J, Pijpers L, Johnstone RW, Kearney CJ, Oliaro J. Freeman AJ, et al. Among authors: ramsbottom km. Cell Rep. 2019 Sep 10;28(11):2784-2794.e5. doi: 10.1016/j.celrep.2019.08.017. Cell Rep. 2019. PMID: 31509742 Free article.
BET Inhibition Enhances TNF-Mediated Antitumor Immunity.
Wellinger LC, Hogg SJ, Newman DM, Friess T, Geiss D, Michie J, Ramsbottom KM, Bacac M, Fauti T, Marbach D, Jarassier L, Thienger P, Paehler A, Cluse LA, Kearney CJ, Vervoort SJ, Trapani JA, Oliaro J, Shortt J, Ruefli-Brasse A, Rohle D, Johnstone RW. Wellinger LC, et al. Among authors: ramsbottom km. Cancer Immunol Res. 2022 Jan;10(1):87-107. doi: 10.1158/2326-6066.CIR-21-0224. Epub 2021 Nov 15. Cancer Immunol Res. 2022. PMID: 34782346
NKG7 Enhances CD8+ T Cell Synapse Efficiency to Limit Inflammation.
Lelliott EJ, Ramsbottom KM, Dowling MR, Shembrey C, Noori T, Kearney CJ, Michie J, Parish IA, Jordan MA, Baxter AG, Young ND, Brennan AJ, Oliaro J. Lelliott EJ, et al. Among authors: ramsbottom km. Front Immunol. 2022 Jul 6;13:931630. doi: 10.3389/fimmu.2022.931630. eCollection 2022. Front Immunol. 2022. PMID: 35874669 Free PMC article.
A method for detecting intracellular perforin in mouse lymphocytes.
Brennan AJ, House IG, Oliaro J, Ramsbottom KM, Hagn M, Yagita H, Trapani JA, Voskoboinik I. Brennan AJ, et al. Among authors: ramsbottom km. J Immunol. 2014 Dec 1;193(11):5744-50. doi: 10.4049/jimmunol.1402207. Epub 2014 Oct 27. J Immunol. 2014. PMID: 25348626
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