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Page 1
Characterization of CFTR mutations in people with cystic fibrosis and severe liver disease who are not eligible for CFTR modulators.
Colombo C, Ramm GA, Lindblad A, Corti F, Porcaro L, Alghisi F, Asherova I, Evans H, Kashirskaya N, Kondratyeva E, Lewindon PJ, de Monestrol I, Oliver M, Ooi CY, Padoan R, Shankar S, Alicandro G. Colombo C, et al. Among authors: ramm ga. J Cyst Fibros. 2023 Mar;22(2):263-265. doi: 10.1016/j.jcf.2023.01.012. Epub 2023 Feb 2. J Cyst Fibros. 2023. PMID: 36739240
The heavy subunit of ferritin stimulates NLRP3 inflammasomes in hepatic stellate cells through ICAM-1 to drive hepatic inflammation.
Fernandez-Rojo MA, Pearen MA, Burgess AG, Ikonomopoulou MP, Hoang-Le D, Genz B, Saggiomo SL, Nawaratna SSK, Poli M, Reissmann R, Gobert GN, Deutsch U, Engelhardt B, Brooks AJ, Jones A, Arosio P, Ramm GA. Fernandez-Rojo MA, et al. Among authors: ramm ga. Sci Signal. 2024 Apr 2;17(830):eade4335. doi: 10.1126/scisignal.ade4335. Epub 2024 Apr 2. Sci Signal. 2024. PMID: 38564492
Single-nucleus RNA sequencing of pre-malignant liver reveals disease-associated hepatocyte state with HCC prognostic potential.
Carlessi R, Denisenko E, Boslem E, Köhn-Gaone J, Main N, Abu Bakar NDB, Shirolkar GD, Jones M, Beasley AB, Poppe D, Dwyer BJ, Jackaman C, Tjiam MC, Lister R, Karin M, Fallowfield JA, Kendall TJ, Forbes SJ, Gray ES, Olynyk JK, Yeoh G, Forrest ARR, Ramm GA, Febbraio MA, Tirnitz-Parker JEE. Carlessi R, et al. Among authors: ramm ga. Cell Genom. 2023 Apr 13;3(5):100301. doi: 10.1016/j.xgen.2023.100301. eCollection 2023 May 10. Cell Genom. 2023. PMID: 37228755 Free PMC article.
Hemochromatosis.
Olynyk JK, Ramm GA. Olynyk JK, et al. Among authors: ramm ga. N Engl J Med. 2022 Dec 8;387(23):2159-2170. doi: 10.1056/NEJMra2119758. N Engl J Med. 2022. PMID: 36477033 Review. No abstract available.
The structural conformation of the tachykinin domain drives the anti-tumoural activity of an octopus peptide in melanoma BRAFV600E.
Moral-Sanz J, Fernandez-Rojo MA, Colmenarejo G, Kurdyukov S, Brust A, Ragnarsson L, Andersson Å, Vila SF, Cabezas-Sainz P, Wilhelm P, Vela-Sebastián A, Fernández-Carrasco I, Chin YKY, López-Mancheño Y, Smallwood TB, Clark RJ, Fry BG, King GF, Ramm GA, Alewood PF, Lewis RJ, Mulvenna JP, Boyle GM, Sanchez LE, Neely GG, Miles JJ, Ikonomopoulou MP. Moral-Sanz J, et al. Among authors: ramm ga. Br J Pharmacol. 2022 Oct;179(20):4878-4896. doi: 10.1111/bph.15923. Epub 2022 Jul 29. Br J Pharmacol. 2022. PMID: 35818835 Free article.
180 results