Ramani VC - Search Results

1

Immune-stimulating antibody conjugates elicit robust myeloid activation and durable antitumor immunity.

Ackerman SE, Pearson CI, Gregorio JD, Gonzalez JC, Kenkel JA, Hartmann FJ, Luo A, Ho PY, LeBlanc H, Blum LK, Kimmey SC, Luo A, Nguyen ML, Paik JC, Sheu LY, Ackerman B, Lee A, Li H, Melrose J, Laura RP, Ramani VC, Henning KA, Jackson DY, Safina BS, Yonehiro G, Devens BH, Carmi Y, Chapin SJ, Bendall SC, Kowanetz M, Dornan D, Engleman EG, Alonso MN. Ackerman SE, et al. Among authors: ramani vc. Nat Cancer. 2021 Jan;2(1):18-33. doi: 10.1038/s43018-020-00136-x. Epub 2020 Dec 7. Nat Cancer. 2021. PMID: 35121890 Free PMC article.

2

Kallikrein 7 enhances pancreatic cancer cell invasion by shedding E-cadherin.

Johnson SK, Ramani VC, Hennings L, Haun RS. Johnson SK, et al. Among authors: ramani vc. Cancer. 2007 May 1;109(9):1811-20. doi: 10.1002/cncr.22606. Cancer. 2007. PMID: 17354228 Free article.

3

SST0001, a chemically modified heparin, inhibits myeloma growth and angiogenesis via disruption of the heparanase/syndecan-1 axis.

Ritchie JP, Ramani VC, Ren Y, Naggi A, Torri G, Casu B, Penco S, Pisano C, Carminati P, Tortoreto M, Zunino F, Vlodavsky I, Sanderson RD, Yang Y. Ritchie JP, et al. Among authors: ramani vc. Clin Cancer Res. 2011 Mar 15;17(6):1382-93. doi: 10.1158/1078-0432.CCR-10-2476. Epub 2011 Jan 21. Clin Cancer Res. 2011. PMID: 21257720 Free PMC article.

4

The extracellular matrix protein fibronectin is a substrate for kallikrein 7.

Ramani VC, Haun RS. Ramani VC, et al. Biochem Biophys Res Commun. 2008 May 16;369(4):1169-73. doi: 10.1016/j.bbrc.2008.03.021. Epub 2008 Mar 14. Biochem Biophys Res Commun. 2008. PMID: 18343220

5

Expression of kallikrein 7 diminishes pancreatic cancer cell adhesion to vitronectin and enhances urokinase-type plasminogen activator receptor shedding.

Ramani VC, Haun RS. Ramani VC, et al. Pancreas. 2008 Nov;37(4):399-404. doi: 10.1097/MPA.0b013e31817f76f7. Pancreas. 2008. PMID: 18953252

6

Desmoglein 2 is a substrate of kallikrein 7 in pancreatic cancer.

Ramani VC, Hennings L, Haun RS. Ramani VC, et al. BMC Cancer. 2008 Dec 17;8:373. doi: 10.1186/1471-2407-8-373. BMC Cancer. 2008. PMID: 19091121 Free PMC article.

7

Proteolytic action of kallikrein-related peptidase 7 produces unique active matrix metalloproteinase-9 lacking the C-terminal hemopexin domains.

Ramani VC, Kaushal GP, Haun RS. Ramani VC, et al. Biochim Biophys Acta. 2011 Aug;1813(8):1525-31. doi: 10.1016/j.bbamcr.2011.05.007. Epub 2011 May 17. Biochim Biophys Acta. 2011. PMID: 21616098 Free PMC article.

8

Heparanase enhances local and systemic osteolysis in multiple myeloma by upregulating the expression and secretion of RANKL.

Yang Y, Ren Y, Ramani VC, Nan L, Suva LJ, Sanderson RD. Yang Y, et al. Among authors: ramani vc. Cancer Res. 2010 Nov 1;70(21):8329-38. doi: 10.1158/0008-5472.CAN-10-2179. Epub 2010 Oct 26. Cancer Res. 2010. PMID: 20978204 Free PMC article.

9

Heparanase plays a dual role in driving hepatocyte growth factor (HGF) signaling by enhancing HGF expression and activity.

Ramani VC, Yang Y, Ren Y, Nan L, Sanderson RD. Ramani VC, et al. J Biol Chem. 2011 Feb 25;286(8):6490-9. doi: 10.1074/jbc.M110.183277. Epub 2010 Dec 3. J Biol Chem. 2011. PMID: 21131364 Free PMC article.

10

The heparanase/syndecan-1 axis in cancer: mechanisms and therapies.

Ramani VC, Purushothaman A, Stewart MD, Thompson CA, Vlodavsky I, Au JL, Sanderson RD. Ramani VC, et al. FEBS J. 2013 May;280(10):2294-306. doi: 10.1111/febs.12168. Epub 2013 Mar 4. FEBS J. 2013. PMID: 23374281 Free PMC article. Review.

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