Ramanathan L - Search Results

1

Expression, purification, stability optimization and characterization of human Aurora B kinase domain from E. coli.

Sheth PR, Ramanathan L, Ranchod A, Basso AD, Barrett D, Zhao J, Gray K, Liu YH, Zhang R, Le HV. Sheth PR, et al. Among authors: ramanathan l. Arch Biochem Biophys. 2010 Nov 15;503(2):191-201. doi: 10.1016/j.abb.2010.08.004. Epub 2010 Aug 10. Arch Biochem Biophys. 2010. PMID: 20699085

2

Purification and characterization of truncated human AMPK alpha 2 beta 2 gamma 3 heterotrimer from baculovirus-infected insect cells.

Ramanathan L, Sheth PR, Ogas P, Xiao L, Le HV. Ramanathan L, et al. Protein Expr Purif. 2010 Mar;70(1):13-22. doi: 10.1016/j.pep.2009.10.007. Epub 2009 Oct 30. Protein Expr Purif. 2010. PMID: 19836452

3

Probing the substrate specificity of hepatitis C virus NS3 serine protease by using synthetic peptides.

Zhang R, Durkin J, Windsor WT, McNemar C, Ramanathan L, Le HV. Zhang R, et al. Among authors: ramanathan l. J Virol. 1997 Aug;71(8):6208-13. doi: 10.1128/JVI.71.8.6208-6213.1997. J Virol. 1997. PMID: 9223519 Free PMC article.

4

Serine protease of hepatitis C virus expressed in insect cells as the NS3/4A complex.

Sali DL, Ingram R, Wendel M, Gupta D, McNemar C, Tsarbopoulos A, Chen JW, Hong Z, Chase R, Risano C, Zhang R, Yao N, Kwong AD, Ramanathan L, Le HV, Weber PC. Sali DL, et al. Among authors: ramanathan l. Biochemistry. 1998 Mar 10;37(10):3392-401. doi: 10.1021/bi972010r. Biochemistry. 1998. PMID: 9521660

5

Selective proteolytic cleavage of recombinant human interleukin 4. Evidence for a critical role of the C-terminus.

Le HV, Seelig GF, Syto R, Ramanathan L, Windsor WT, Borkowski D, Trotta PP. Le HV, et al. Among authors: ramanathan l. Biochemistry. 1991 Oct 8;30(40):9576-82. doi: 10.1021/bi00104a003. Biochemistry. 1991. PMID: 1911743

6

Immunochemical mapping of domains in human interleukin 4 recognized by neutralizing monoclonal antibodies.

Ramanathan L, Ingram R, Sullivan L, Greenberg R, Reim R, Trotta PP, Le HV. Ramanathan L, et al. Biochemistry. 1993 Apr 13;32(14):3549-56. doi: 10.1021/bi00065a005. Biochemistry. 1993. PMID: 7682108

7

Structure-guided discovery of cyclin-dependent kinase inhibitors.

Fischmann TO, Hruza A, Duca JS, Ramanathan L, Mayhood T, Windsor WT, Le HV, Guzi TJ, Dwyer MP, Paruch K, Doll RJ, Lees E, Parry D, Seghezzi W, Madison V. Fischmann TO, et al. Among authors: ramanathan l. Biopolymers. 2008 May;89(5):372-9. doi: 10.1002/bip.20868. Biopolymers. 2008. PMID: 17937404

8

Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core.

Yu T, Tagat JR, Kerekes AD, Doll RJ, Zhang Y, Xiao Y, Esposite S, Belanger DB, Curran PJ, Mandal AK, Siddiqui MA, Shih NY, Basso AD, Liu M, Gray K, Tevar S, Jones J, Lee S, Liang L, Ponery S, Smith EB, Hruza A, Voigt J, Ramanathan L, Prosise W, Hu M. Yu T, et al. Among authors: ramanathan l. ACS Med Chem Lett. 2010 Jun 7;1(5):214-8. doi: 10.1021/ml100063w. eCollection 2010 Aug 12. ACS Med Chem Lett. 2010. PMID: 24900197 Free PMC article.

9

Screening and rank ordering of reversible mechanism-based inhibitors of hepatitis C virus NS3 protease using electrospray ionization mass spectrometry.

Liu YH, Ramanathan L, Malcolm B, Njoroge G, Chan TY, Pramanik BN. Liu YH, et al. Among authors: ramanathan l. J Mass Spectrom. 2011 Aug;46(8):764-71. doi: 10.1002/jms.1948. J Mass Spectrom. 2011. PMID: 21766396

10

Key steps in the structure-based optimization of the hepatitis C virus NS3/4A protease inhibitor SCH503034.

Madison V, Prongay AJ, Guo Z, Yao N, Pichardo J, Fischmann T, Strickland C, Myers J Jr, Weber PC, Beyer BM, Ingram R, Hong Z, Prosise WW, Ramanathan L, Taremi SS, Yarosh-Tomaine T, Zhang R, Senior M, Yang RS, Malcolm B, Arasappan A, Bennett F, Bogen SL, Chen K, Jao E, Liu YT, Lovey RG, Saksena AK, Venkatraman S, Girijavallabhan V, Njoroge FG. Madison V, et al. Among authors: ramanathan l. J Synchrotron Radiat. 2008 May;15(Pt 3):204-7. doi: 10.1107/S0909049507064229. Epub 2008 Apr 18. J Synchrotron Radiat. 2008. PMID: 18421139 Free PMC article.

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