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426 results

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Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis.
Wiley CD, Sharma R, Davis SS, Lopez-Dominguez JA, Mitchell KP, Wiley S, Alimirah F, Kim DE, Payne T, Rosko A, Aimontche E, Deshpande SM, Neri F, Kuehnemann C, Demaria M, Ramanathan A, Campisi J. Wiley CD, et al. Among authors: ramanathan a. Cell Metab. 2021 Jun 1;33(6):1124-1136.e5. doi: 10.1016/j.cmet.2021.03.008. Epub 2021 Apr 2. Cell Metab. 2021. PMID: 33811820 Free PMC article.
Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype.
Wiley CD, Velarde MC, Lecot P, Liu S, Sarnoski EA, Freund A, Shirakawa K, Lim HW, Davis SS, Ramanathan A, Gerencser AA, Verdin E, Campisi J. Wiley CD, et al. Among authors: ramanathan a. Cell Metab. 2016 Feb 9;23(2):303-14. doi: 10.1016/j.cmet.2015.11.011. Epub 2015 Dec 10. Cell Metab. 2016. PMID: 26686024 Free PMC article.
A novel AhR ligand, 2AI, protects the retina from environmental stress.
Gutierrez MA, Davis SS, Rosko A, Nguyen SM, Mitchell KP, Mateen S, Neves J, Garcia TY, Mooney S, Perdew GH, Hubbard TD, Lamba DA, Ramanathan A. Gutierrez MA, et al. Among authors: ramanathan a. Sci Rep. 2016 Jul 1;6:29025. doi: 10.1038/srep29025. Sci Rep. 2016. PMID: 27364765 Free PMC article.
JNK modifies neuronal metabolism to promote proteostasis and longevity.
Wang L, Davis SS, Borch Jensen M, Rodriguez-Fernandez IA, Apaydin C, Juhasz G, Gibson BW, Schilling B, Ramanathan A, Ghaemmaghami S, Jasper H. Wang L, et al. Among authors: ramanathan a. Aging Cell. 2019 Jun;18(3):e12849. doi: 10.1111/acel.12849. Epub 2019 Feb 27. Aging Cell. 2019. PMID: 30810280 Free PMC article.
Secretion of leukotrienes by senescent lung fibroblasts promotes pulmonary fibrosis.
Wiley CD, Brumwell AN, Davis SS, Jackson JR, Valdovinos A, Calhoun C, Alimirah F, Castellanos CA, Ruan R, Wei Y, Chapman HA, Ramanathan A, Campisi J, Jourdan Le Saux C. Wiley CD, et al. Among authors: ramanathan a. JCI Insight. 2019 Dec 19;4(24):e130056. doi: 10.1172/jci.insight.130056. JCI Insight. 2019. PMID: 31687975 Free PMC article.
The Aging Metabolome-Biomarkers to Hub Metabolites.
Sharma R, Ramanathan A. Sharma R, et al. Among authors: ramanathan a. Proteomics. 2020 Mar;20(5-6):e1800407. doi: 10.1002/pmic.201800407. Proteomics. 2020. PMID: 32068959 Free PMC article. Review.
Aryl hydrocarbon receptor blocks aging-induced senescence in the liver and fibroblast cells.
Nacarino-Palma A, Rico-Leo EM, Campisi J, Ramanathan A, González-Rico FJ, Rejano-Gordillo CM, Ordiales-Talavero A, Merino JM, Fernández-Salguero PM. Nacarino-Palma A, et al. Among authors: ramanathan a. Aging (Albany NY). 2022 May 26;14(10):4281-4304. doi: 10.18632/aging.204103. Epub 2022 May 26. Aging (Albany NY). 2022. PMID: 35619220 Free PMC article.
426 results