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Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.
Sci Rep. 2016 Jan 13;6:18851. doi: 10.1038/srep18851.
Sci Rep. 2016.
PMID: 26758806
Free PMC article.
T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4.
Coles CH, McMurran C, Lloyd A, Hock M, Hibbert L, Raman MCC, Hayes C, Lupardus P, Cole DK, Harper S.
Coles CH, et al. Among authors: raman mcc.
J Biol Chem. 2020 Aug 14;295(33):11486-11494. doi: 10.1074/jbc.RA120.014016. Epub 2020 Jun 12.
J Biol Chem. 2020.
PMID: 32532817
Free PMC article.
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The external aldimine form of serine palmitoyltransferase: structural, kinetic, and spectroscopic analysis of the wild-type enzyme and HSAN1 mutant mimics.
Raman MCC, Johnson KA, Yard BA, Lowther J, Carter LG, Naismith JH, Campopiano DJ.
Raman MCC, et al.
J Biol Chem. 2009 Jun 19;284(25):17328-17339. doi: 10.1074/jbc.M109.008680. Epub 2009 Apr 17.
J Biol Chem. 2009.
PMID: 19376777
Free PMC article.
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Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation.
Lowther J, Yard BA, Johnson KA, Carter LG, Bhat VT, Raman MC, Clarke DJ, Ramakers B, McMahon SA, Naismith JH, Campopiano DJ.
Lowther J, et al. Among authors: raman mc.
Mol Biosyst. 2010 Sep;6(9):1682-93. doi: 10.1039/c003743e. Epub 2010 May 5.
Mol Biosyst. 2010.
PMID: 20445930
Free PMC article.
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The serine palmitoyltransferase from Sphingomonas wittichii RW1: An interesting link to an unusual acyl carrier protein.
Raman MC, Johnson KA, Clarke DJ, Naismith JH, Campopiano DJ.
Raman MC, et al.
Biopolymers. 2010 Sep;93(9):811-22. doi: 10.1002/bip.21482.
Biopolymers. 2010.
PMID: 20578000
Free article.
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Role of a conserved arginine residue during catalysis in serine palmitoyltransferase.
Lowther J, Charmier G, Raman MC, Ikushiro H, Hayashi H, Campopiano DJ.
Lowther J, et al. Among authors: raman mc.
FEBS Lett. 2011 Jun 23;585(12):1729-34. doi: 10.1016/j.febslet.2011.04.013. Epub 2011 Apr 18.
FEBS Lett. 2011.
PMID: 21514297
Free article.
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Gastro-oesophageal reflux is more prevalent in Western dyspeptics: a prospective comparison of British and South-East Asian patients with dyspepsia.
Mahadeva S, Raman MC, Ford AC, Follows M, Axon AT, Goh KL, Moayyedi P.
Mahadeva S, et al. Among authors: raman mc.
Aliment Pharmacol Ther. 2005 Jun 15;21(12):1483-90. doi: 10.1111/j.1365-2036.2005.02455.x.
Aliment Pharmacol Ther. 2005.
PMID: 15948816
Free article.
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