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Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells.
Eriksson M, Peña-Martínez P, Ramakrishnan R, Chapellier M, Högberg C, Glowacki G, Orsmark-Pietras C, Velasco-Hernández T, Lazarević VL, Juliusson G, Cammenga J, Mulloy JC, Richter J, Fioretos T, Ebert BL, Järås M. Eriksson M, et al. Among authors: ramakrishnan r. Blood Adv. 2017 Oct 18;1(23):2046-2057. doi: 10.1182/bloodadvances.2017006148. eCollection 2017 Oct 24. Blood Adv. 2017. PMID: 29296851 Free PMC article.
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells.
Chapellier M, Peña-Martínez P, Ramakrishnan R, Eriksson M, Talkhoncheh MS, Orsmark-Pietras C, Lilljebjörn H, Högberg C, Hagström-Andersson A, Fioretos T, Larsson J, Järås M. Chapellier M, et al. Among authors: ramakrishnan r. Haematologica. 2019 Oct;104(10):2006-2016. doi: 10.3324/haematol.2018.192062. Epub 2019 Feb 28. Haematologica. 2019. PMID: 30819903 Free PMC article.
CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia.
Ramakrishnan R, Peña-Martínez P, Agarwal P, Rodriguez-Zabala M, Chapellier M, Högberg C, Eriksson M, Yudovich D, Shah M, Ehinger M, Nilsson B, Larsson J, Hagström-Andersson A, Ebert BL, Bhatia R, Järås M. Ramakrishnan R, et al. Cell Rep. 2020 May 26;31(8):107684. doi: 10.1016/j.celrep.2020.107684. Cell Rep. 2020. PMID: 32460032 Free PMC article.
Yippee like 4 (Ypel4) is essential for normal mouse red blood cell membrane integrity.
Mattebo A, Sen T, Jassinskaja M, Pimková K, Prieto González-Albo I, Alattar AG, Ramakrishnan R, Lang S, Järås M, Hansson J, Soneji S, Singbrant S, van den Akker E, Flygare J. Mattebo A, et al. Among authors: ramakrishnan r. Sci Rep. 2021 Aug 5;11(1):15898. doi: 10.1038/s41598-021-95291-1. Sci Rep. 2021. PMID: 34354145 Free PMC article.
Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity.
Rodriguez-Zabala M, Ramakrishnan R, Reinbach K, Ghosh S, Oburoglu L, Falqués-Costa A, Bellamkonda K, Ehinger M, Peña-Martínez P, Puente-Moncada N, Lilljebjörn H, Cammenga J, Pronk CJ, Lazarevic V, Fioretos T, Hagström-Andersson AK, Woods NB, Järås M. Rodriguez-Zabala M, et al. Among authors: ramakrishnan r. Blood Adv. 2023 Sep 26;7(18):5382-5395. doi: 10.1182/bloodadvances.2023009967. Blood Adv. 2023. PMID: 37505194 Free PMC article.
Activation of endogenous retroviruses during brain development causes an inflammatory response.
Jönsson ME, Garza R, Sharma Y, Petri R, Södersten E, Johansson JG, Johansson PA, Atacho DA, Pircs K, Madsen S, Yudovich D, Ramakrishnan R, Holmberg J, Larsson J, Jern P, Jakobsson J. Jönsson ME, et al. Among authors: ramakrishnan r. EMBO J. 2021 May 3;40(9):e106423. doi: 10.15252/embj.2020106423. Epub 2021 Mar 1. EMBO J. 2021. PMID: 33644903 Free PMC article.
BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells.
Gomes Fernandes M, Dries R, Roost MS, Semrau S, de Melo Bernardo A, Davis RP, Ramakrishnan R, Szuhai K, Maas E, Umans L, Abon Escalona V, Salvatori D, Deforce D, Van Criekinge W, Huylebroeck D, Mummery C, Zwijsen A, de Sousa Lopes SM. Gomes Fernandes M, et al. Among authors: ramakrishnan r. Stem Cell Reports. 2016 Jan 12;6(1):85-94. doi: 10.1016/j.stemcr.2015.11.012. Epub 2015 Dec 17. Stem Cell Reports. 2016. PMID: 26711875 Free PMC article.
747 results