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Chronic exposure to excess iron promotes EMT and cancer via p53 loss in pancreatic cancer.
Bhutia YD, Ogura J, Grippo PJ, Torres C, Sato T, Wachtel M, Ramachandran S, Babu E, Sivaprakasam S, Rajasekaran D, Schniers B, On N, Smoot L, Thangaraju M, Gnana-Prakasam JP, Ganapathy V. Bhutia YD, et al. Among authors: ramachandran s. Asian J Pharm Sci. 2020 Mar;15(2):237-251. doi: 10.1016/j.ajps.2020.02.003. Epub 2020 Mar 5. Asian J Pharm Sci. 2020. PMID: 32373202 Free PMC article.
SLC6A14 (ATB0,+) protein, a highly concentrative and broad specific amino acid transporter, is a novel and effective drug target for treatment of estrogen receptor-positive breast cancer.
Karunakaran S, Ramachandran S, Coothankandaswamy V, Elangovan S, Babu E, Periyasamy-Thandavan S, Gurav A, Gnanaprakasam JP, Singh N, Schoenlein PV, Prasad PD, Thangaraju M, Ganapathy V. Karunakaran S, et al. Among authors: ramachandran s. J Biol Chem. 2011 Sep 9;286(36):31830-8. doi: 10.1074/jbc.M111.229518. Epub 2011 Jul 19. J Biol Chem. 2011. PMID: 21771784 Free PMC article.
SIRT1 is essential for oncogenic signaling by estrogen/estrogen receptor α in breast cancer.
Elangovan S, Ramachandran S, Venkatesan N, Ananth S, Gnana-Prakasam JP, Martin PM, Browning DD, Schoenlein PV, Prasad PD, Ganapathy V, Thangaraju M. Elangovan S, et al. Among authors: ramachandran s. Cancer Res. 2011 Nov 1;71(21):6654-64. doi: 10.1158/0008-5472.CAN-11-1446. Epub 2011 Sep 15. Cancer Res. 2011. PMID: 21920899 Free PMC article.
Molecular mechanism of SLC5A8 inactivation in breast cancer.
Elangovan S, Pathania R, Ramachandran S, Ananth S, Padia RN, Srinivas SR, Babu E, Hawthorn L, Schoenlein PV, Boettger T, Smith SB, Prasad PD, Ganapathy V, Thangaraju M. Elangovan S, et al. Among authors: ramachandran s. Mol Cell Biol. 2013 Oct;33(19):3920-35. doi: 10.1128/MCB.01702-12. Epub 2013 Aug 5. Mol Cell Biol. 2013. PMID: 23918800 Free PMC article.
DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis.
Pathania R, Ramachandran S, Elangovan S, Padia R, Yang P, Cinghu S, Veeranan-Karmegam R, Arjunan P, Gnana-Prakasam JP, Sadanand F, Pei L, Chang CS, Choi JH, Shi H, Manicassamy S, Prasad PD, Sharma S, Ganapathy V, Jothi R, Thangaraju M. Pathania R, et al. Among authors: ramachandran s. Nat Commun. 2015 Apr 24;6:6910. doi: 10.1038/ncomms7910. Nat Commun. 2015. PMID: 25908435 Free PMC article.
1,689 results