Ralle M - Search Results

1

Connecting copper and cancer: from transition metal signalling to metalloplasia.

Ge EJ, Bush AI, Casini A, Cobine PA, Cross JR, DeNicola GM, Dou QP, Franz KJ, Gohil VM, Gupta S, Kaler SG, Lutsenko S, Mittal V, Petris MJ, Polishchuk R, Ralle M, Schilsky ML, Tonks NK, Vahdat LT, Van Aelst L, Xi D, Yuan P, Brady DC, Chang CJ. Ge EJ, et al. Among authors: ralle m. Nat Rev Cancer. 2022 Feb;22(2):102-113. doi: 10.1038/s41568-021-00417-2. Epub 2021 Nov 11. Nat Rev Cancer. 2022. PMID: 34764459 Free PMC article. Review.

2

X-ray absorption spectroscopy of the copper chaperone HAH1 reveals a linear two-coordinate Cu(I) center capable of adduct formation with exogenous thiols and phosphines.

Ralle M, Lutsenko S, Blackburn NJ. Ralle M, et al. J Biol Chem. 2003 Jun 20;278(25):23163-70. doi: 10.1074/jbc.M303474200. Epub 2003 Apr 9. J Biol Chem. 2003. PMID: 12686548 Free article.

3

The N-terminal metal-binding site 2 of the Wilson's Disease Protein plays a key role in the transfer of copper from Atox1.

Walker JM, Huster D, Ralle M, Morgan CT, Blackburn NJ, Lutsenko S. Walker JM, et al. Among authors: ralle m. J Biol Chem. 2004 Apr 9;279(15):15376-84. doi: 10.1074/jbc.M400053200. Epub 2004 Jan 30. J Biol Chem. 2004. PMID: 14754885 Free article.

4

Copper transfer to the N-terminal domain of the Wilson disease protein (ATP7B): X-ray absorption spectroscopy of reconstituted and chaperone-loaded metal binding domains and their interaction with exogenous ligands.

Ralle M, Lutsenko S, Blackburn NJ. Ralle M, et al. J Inorg Biochem. 2004 May;98(5):765-74. doi: 10.1016/j.jinorgbio.2004.02.009. J Inorg Biochem. 2004. PMID: 15134922

5

High copper selectively alters lipid metabolism and cell cycle machinery in the mouse model of Wilson disease.

Huster D, Purnat TD, Burkhead JL, Ralle M, Fiehn O, Stuckert F, Olson NE, Teupser D, Lutsenko S. Huster D, et al. Among authors: ralle m. J Biol Chem. 2007 Mar 16;282(11):8343-55. doi: 10.1074/jbc.M607496200. Epub 2007 Jan 7. J Biol Chem. 2007. PMID: 17205981 Free article.

6

Quantitative imaging of metals in tissues.

Ralle M, Lutsenko S. Ralle M, et al. Biometals. 2009 Feb;22(1):197-205. doi: 10.1007/s10534-008-9200-5. Epub 2009 Jan 7. Biometals. 2009. PMID: 19130257 Review.

7

The loop connecting metal-binding domains 3 and 4 of ATP7B is a target of a kinase-mediated phosphorylation.

Bartee MY, Ralle M, Lutsenko S. Bartee MY, et al. Among authors: ralle m. Biochemistry. 2009 Jun 23;48(24):5573-81. doi: 10.1021/bi900325k. Biochemistry. 2009. PMID: 19405516 Free PMC article.

8

Interactions between copper-binding sites determine the redox status and conformation of the regulatory N-terminal domain of ATP7B.

LeShane ES, Shinde U, Walker JM, Barry AN, Blackburn NJ, Ralle M, Lutsenko S. LeShane ES, et al. Among authors: ralle m. J Biol Chem. 2010 Feb 26;285(9):6327-36. doi: 10.1074/jbc.M109.074633. Epub 2009 Dec 23. J Biol Chem. 2010. PMID: 20032459 Free PMC article.

9

Wilson disease at a single cell level: intracellular copper trafficking activates compartment-specific responses in hepatocytes.

Ralle M, Huster D, Vogt S, Schirrmeister W, Burkhead JL, Capps TR, Gray L, Lai B, Maryon E, Lutsenko S. Ralle M, et al. J Biol Chem. 2010 Oct 1;285(40):30875-83. doi: 10.1074/jbc.M110.114447. Epub 2010 Jul 20. J Biol Chem. 2010. PMID: 20647314 Free PMC article.

10

Elevated copper remodels hepatic RNA processing machinery in the mouse model of Wilson's disease.

Burkhead JL, Ralle M, Wilmarth P, David L, Lutsenko S. Burkhead JL, et al. Among authors: ralle m. J Mol Biol. 2011 Feb 11;406(1):44-58. doi: 10.1016/j.jmb.2010.12.001. Epub 2010 Dec 10. J Mol Biol. 2011. PMID: 21146535 Free PMC article.

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