Rakyan VK - Search Results

1

Genetic variation at mouse and human ribosomal DNA influences associated epigenetic states.

Rodriguez-Algarra F, Seaborne RAE, Danson AF, Yildizoglu S, Yoshikawa H, Law PP, Ahmad Z, Maudsley VA, Brew A, Holmes N, Ochôa M, Hodgkinson A, Marzi SJ, Pradeepa MM, Loose M, Holland ML, Rakyan VK. Rodriguez-Algarra F, et al. Among authors: rakyan vk. Genome Biol. 2022 Feb 14;23(1):54. doi: 10.1186/s13059-022-02617-x. Genome Biol. 2022. PMID: 35164830 Free PMC article.

2

An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs).

Rakyan VK, Down TA, Thorne NP, Flicek P, Kulesha E, Gräf S, Tomazou EM, Bäckdahl L, Johnson N, Herberth M, Howe KL, Jackson DK, Miretti MM, Fiegler H, Marioni JC, Birney E, Hubbard TJ, Carter NP, Tavaré S, Beck S. Rakyan VK, et al. Genome Res. 2008 Sep;18(9):1518-29. doi: 10.1101/gr.077479.108. Epub 2008 Jun 24. Genome Res. 2008. PMID: 18577705 Free PMC article.

3

Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains.

Rakyan VK, Down TA, Maslau S, Andrew T, Yang TP, Beyan H, Whittaker P, McCann OT, Finer S, Valdes AM, Leslie RD, Deloukas P, Spector TD. Rakyan VK, et al. Genome Res. 2010 Apr;20(4):434-9. doi: 10.1101/gr.103101.109. Epub 2010 Mar 10. Genome Res. 2010. PMID: 20219945 Free PMC article.

4

The hunt for the epiallele.

Finer S, Holland ML, Nanty L, Rakyan VK. Finer S, et al. Among authors: rakyan vk. Environ Mol Mutagen. 2011 Jan;52(1):1-11. doi: 10.1002/em.20590. Environ Mol Mutagen. 2011. PMID: 20839222 Review.

5

Epigenome-wide association studies for common human diseases.

Rakyan VK, Down TA, Balding DJ, Beck S. Rakyan VK, et al. Nat Rev Genet. 2011 Jul 12;12(8):529-41. doi: 10.1038/nrg3000. Nat Rev Genet. 2011. PMID: 21747404 Free PMC article. Review.

6

Comparative methylomics reveals gene-body H3K36me3 in Drosophila predicts DNA methylation and CpG landscapes in other invertebrates.

Nanty L, Carbajosa G, Heap GA, Ratnieks F, van Heel DA, Down TA, Rakyan VK. Nanty L, et al. Among authors: rakyan vk. Genome Res. 2011 Nov;21(11):1841-50. doi: 10.1101/gr.121640.111. Epub 2011 Sep 22. Genome Res. 2011. PMID: 21940836 Free PMC article.

7

Identification of type 1 diabetes-associated DNA methylation variable positions that precede disease diagnosis.

Rakyan VK, Beyan H, Down TA, Hawa MI, Maslau S, Aden D, Daunay A, Busato F, Mein CA, Manfras B, Dias KR, Bell CG, Tost J, Boehm BO, Beck S, Leslie RD. Rakyan VK, et al. PLoS Genet. 2011 Sep;7(9):e1002300. doi: 10.1371/journal.pgen.1002300. Epub 2011 Sep 29. PLoS Genet. 2011. PMID: 21980303 Free PMC article.

8

Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans.

Beyan H, Down TA, Ramagopalan SV, Uvebrant K, Nilsson A, Holland ML, Gemma C, Giovannoni G, Boehm BO, Ebers GC, Lernmark Å, Cilio CM, Leslie RD, Rakyan VK. Beyan H, et al. Among authors: rakyan vk. Genome Res. 2012 Nov;22(11):2138-45. doi: 10.1101/gr.134304.111. Epub 2012 Aug 23. Genome Res. 2012. PMID: 22919074 Free PMC article.

9

Transgenerational inheritance of non-genetically determined phenotypes.

Holland ML, Rakyan VK. Holland ML, et al. Among authors: rakyan vk. Biochem Soc Trans. 2013 Jun;41(3):769-76. doi: 10.1042/BST20130043. Biochem Soc Trans. 2013. PMID: 23697936 Review.

10

Inactive or moderately active human promoters are enriched for inter-individual epialleles.

Gemma C, Ramagopalan SV, Down TA, Beyan H, Hawa MI, Holland ML, Hurd PJ, Giovannoni G, Leslie RD, Ebers GC, Rakyan VK. Gemma C, et al. Among authors: rakyan vk. Genome Biol. 2013 May 25;14(5):R43. doi: 10.1186/gb-2013-14-5-r43. Genome Biol. 2013. PMID: 23706135 Free PMC article.

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