An epistatic relationship between the viral protein kinase UL97 and the UL133-UL138 latency locus during the human cytomegalovirus lytic cycle.
Li G, Rak M, Nguyen CC, Umashankar M, Goodrum FD, Kamil JP.
Li G, et al. Among authors: rak m.
J Virol. 2014 Jun;88(11):6047-60. doi: 10.1128/JVI.00447-14. Epub 2014 Mar 12.
J Virol. 2014.
PMID: 24623439
Free PMC article.
Although viral immediate early (IE) gene expression is essential for HCMV lytic replication, the activation of IE gene expression in latently infected cells is not sufficient to result in production of infectious virus. Our findings here and in an accompanying study (M. Um …
Although viral immediate early (IE) gene expression is essential for HCMV lytic replication, the activation of IE gene expression in latentl …