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Page 1
Simulating Intestinal Transporter and Enzyme Activity in a Physiologically Based Pharmacokinetic Model for Tenofovir Disoproxil Fumarate.
Moss DM, Domanico P, Watkins M, Park S, Randolph R, Wring S, Rajoli RKR, Hobson J, Rannard S, Siccardi M, Owen A. Moss DM, et al. Among authors: rajoli rkr. Antimicrob Agents Chemother. 2017 Jun 27;61(7):e00105-17. doi: 10.1128/AAC.00105-17. Print 2017 Jul. Antimicrob Agents Chemother. 2017. PMID: 28416547 Free PMC article.
Chemoprophylactic Assessment of Combined Intranasal SARS-CoV-2 Polymerase and Exonuclease Inhibition in Syrian Golden Hamsters.
Gallardo-Toledo E, Neary M, Sharp J, Herriott J, Kijak E, Bramwell C, Curley P, Arshad U, Pertinez H, Rajoli RKR, Valentijn A, Cox H, Tatham L, Kipar A, Stewart JP, Owen A. Gallardo-Toledo E, et al. Among authors: rajoli rkr. Viruses. 2023 Oct 27;15(11):2161. doi: 10.3390/v15112161. Viruses. 2023. PMID: 38005839 Free PMC article.
Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters.
Box HJ, Sharp J, Pennington SH, Kijak E, Tatham L, Caygill CH, Lopeman RC, Jeffreys LN, Herriott J, Neary M, Valentijn A, Pertinez H, Curley P, Arshad U, Rajoli RKR, Jochmans D, Vangeel L, Neyts J, Chatelain E, Escudié F, Scandale I, Rannard S, Stewart JP, Biagini GA, Owen A. Box HJ, et al. Among authors: rajoli rkr. J Antimicrob Chemother. 2024 Jan 3;79(1):172-178. doi: 10.1093/jac/dkad362. J Antimicrob Chemother. 2024. PMID: 37995258 Free PMC article.
Evaluation of Nafamostat as Chemoprophylaxis for SARS-CoV-2 Infection in Hamsters.
Neary M, Sharp J, Gallardo-Toledo E, Herriott J, Kijak E, Bramwell C, Cox H, Tatham L, Box H, Curley P, Arshad U, Rajoli RKR, Pertinez H, Valentijn A, Dhaliwal K, Mc Caughan F, Hobson J, Rannard S, Kipar A, Stewart JP, Owen A. Neary M, et al. Among authors: rajoli rkr. Viruses. 2023 Aug 15;15(8):1744. doi: 10.3390/v15081744. Viruses. 2023. PMID: 37632086 Free PMC article.
Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research.
Neary M, Arshad U, Tatham L, Pertinez H, Box H, Rajoli RKR, Valentijn A, Sharp J, Rannard SP, Biagini GA, Curley P, Owen A. Neary M, et al. Among authors: rajoli rkr. J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Aug 1;1228:123823. doi: 10.1016/j.jchromb.2023.123823. Epub 2023 Jul 16. J Chromatogr B Analyt Technol Biomed Life Sci. 2023. PMID: 37517355 Free article.
Unlike Chloroquine, Mefloquine Inhibits SARS-CoV-2 Infection in Physiologically Relevant Cells.
Sacramento CQ, Fintelman-Rodrigues N, Dias SSG, Temerozo JR, Da Silva APD, da Silva CS, Blanco C, Ferreira AC, Mattos M, Soares VC, Pereira-Dutra F, Miranda MD, Barreto-Vieira DF, da Silva MAN, Santos SS, Torres M, Chaves OA, Rajoli RKR, Paccanaro A, Owen A, Bou-Habib DC, Bozza PT, Souza TML. Sacramento CQ, et al. Among authors: rajoli rkr. Viruses. 2022 Feb 11;14(2):374. doi: 10.3390/v14020374. Viruses. 2022. PMID: 35215969 Free PMC article.
An Open Label, Adaptive, Phase 1 Trial of High-Dose Oral Nitazoxanide in Healthy Volunteers: An Antiviral Candidate for SARS-CoV-2.
Walker LE, FitzGerald R, Saunders G, Lyon R, Fisher M, Martin K, Eberhart I, Woods C, Ewings S, Hale C, Rajoli RKR, Else L, Dilly-Penchala S, Amara A, Lalloo DG, Jacobs M, Pertinez H, Hatchard P, Waugh R, Lawrence M, Johnson L, Fines K, Reynolds H, Rowland T, Crook R, Okenyi E, Byrne K, Mozgunov P, Jaki T, Khoo S, Owen A, Griffiths G, Fletcher TE; AGILE platform. Walker LE, et al. Among authors: rajoli rkr. Clin Pharmacol Ther. 2022 Mar;111(3):585-594. doi: 10.1002/cpt.2463. Epub 2021 Nov 13. Clin Pharmacol Ther. 2022. PMID: 34699618 Free PMC article. Clinical Trial.
Evaluation of intranasal nafamostat or camostat for SARS-CoV-2 chemoprophylaxis in Syrian golden hamsters.
Neary M, Box H, Sharp J, Tatham L, Curley P, Herriott J, Kijak E, Arshad U, Hobson JJ, Rajoli R, Pertinez H, Valentijn A, Dhaliwal K, McCaughan F, Rannard SP, Kipar A, Stewart JP, Owen A. Neary M, et al. Among authors: rajoli r. bioRxiv [Preprint]. 2021 Jul 8:2021.07.08.451654. doi: 10.1101/2021.07.08.451654. bioRxiv. 2021. PMID: 34268511 Free PMC article. Preprint.
30 results