Rajic Z - Search Results

1

Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics.

Batinic-Haberle I, Rajic Z, Tovmasyan A, Reboucas JS, Ye X, Leong KW, Dewhirst MW, Vujaskovic Z, Benov L, Spasojevic I. Batinic-Haberle I, et al. Among authors: rajic z. Free Radic Biol Med. 2011 Sep 1;51(5):1035-53. doi: 10.1016/j.freeradbiomed.2011.04.046. Epub 2011 May 6. Free Radic Biol Med. 2011. PMID: 21616142 Free PMC article. Review.

2

Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities.

Batinic-Haberle I, Spasojevic I, Tse HM, Tovmasyan A, Rajic Z, St Clair DK, Vujaskovic Z, Dewhirst MW, Piganelli JD. Batinic-Haberle I, et al. Among authors: rajic z. Amino Acids. 2012 Jan;42(1):95-113. doi: 10.1007/s00726-010-0603-6. Epub 2010 May 16. Amino Acids. 2012. PMID: 20473774 Free PMC article. Review.

3

Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site.

Spasojevic I, Kos I, Benov LT, Rajic Z, Fels D, Dedeugd C, Ye X, Vujaskovic Z, Reboucas JS, Leong KW, Dewhirst MW, Batinic-Haberle I. Spasojevic I, et al. Among authors: rajic z. Free Radic Res. 2011 Feb;45(2):188-200. doi: 10.3109/10715762.2010.522575. Epub 2010 Oct 13. Free Radic Res. 2011. PMID: 20942564 Free PMC article.

4

A combination of two antioxidants (an SOD mimic and ascorbate) produces a pro-oxidative effect forcing Escherichia coli to adapt via induction of oxyR regulon.

Batinic-Haberle I, Rajic Z, Benov L. Batinic-Haberle I, et al. Among authors: rajic z. Anticancer Agents Med Chem. 2011 May 1;11(4):329-40. doi: 10.2174/187152011795677562. Anticancer Agents Med Chem. 2011. PMID: 21355843 Free PMC article. Review.

5

Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrins.

Tovmasyan AG, Rajic Z, Spasojevic I, Reboucas JS, Chen X, Salvemini D, Sheng H, Warner DS, Benov L, Batinic-Haberle I. Tovmasyan AG, et al. Among authors: rajic z. Dalton Trans. 2011 Apr 28;40(16):4111-21. doi: 10.1039/c0dt01321h. Epub 2011 Mar 8. Dalton Trans. 2011. PMID: 21384047 Free PMC article.

6

A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity.

Rajic Z, Tovmasyan A, Spasojevic I, Sheng H, Lu M, Li AM, Gralla EB, Warner DS, Benov L, Batinic-Haberle I. Rajic Z, et al. Free Radic Biol Med. 2012 May 1;52(9):1828-34. doi: 10.1016/j.freeradbiomed.2012.02.006. Epub 2012 Feb 13. Free Radic Biol Med. 2012. PMID: 22336516 Free PMC article.

7

Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology.

Tovmasyan A, Weitner T, Sheng H, Lu M, Rajic Z, Warner DS, Spasojevic I, Reboucas JS, Benov L, Batinic-Haberle I. Tovmasyan A, et al. Among authors: rajic z. Inorg Chem. 2013 May 20;52(10):5677-91. doi: 10.1021/ic3012519. Epub 2013 May 6. Inorg Chem. 2013. PMID: 23646875 Free PMC article.

8

Challenges encountered during development of Mn porphyrin-based, potent redox-active drug and superoxide dismutase mimic, MnTnBuOE-2-PyP⁵⁺, and its alkoxyalkyl analogues.

Rajic Z, Tovmasyan A, de Santana OL, Peixoto IN, Spasojevic I, do Monte SA, Ventura E, Rebouças JS, Batinic-Haberle I. Rajic Z, et al. J Inorg Biochem. 2017 Apr;169:50-60. doi: 10.1016/j.jinorgbio.2017.01.003. Epub 2017 Jan 5. J Inorg Biochem. 2017. PMID: 28131001 Free PMC article.

9

Radioprotection of the brain white matter by Mn(III) n-Butoxyethylpyridylporphyrin-based superoxide dismutase mimic MnTnBuOE-2-PyP5+.

Weitzel DH, Tovmasyan A, Ashcraft KA, Rajic Z, Weitner T, Liu C, Li W, Buckley AF, Prasad MR, Young KH, Rodriguiz RM, Wetsel WC, Peters KB, Spasojevic I, Herndon JE 2nd, Batinic-Haberle I, Dewhirst MW. Weitzel DH, et al. Among authors: rajic z. Mol Cancer Ther. 2015 Jan;14(1):70-9. doi: 10.1158/1535-7163.MCT-14-0343. Epub 2014 Oct 15. Mol Cancer Ther. 2015. PMID: 25319393 Free PMC article.

10

Discovery of harmiprims, harmine-primaquine hybrids, as potent and selective anticancer and antimalarial compounds.

Pavić K, Poje G, Pessanha de Carvalho L, Tandarić T, Marinović M, Fontinha D, Held J, Prudêncio M, Piantanida I, Vianello R, Krošl Knežević I, Perković I, Rajić Z. Pavić K, et al. Among authors: rajic z. Bioorg Med Chem. 2024 May 1;105:117734. doi: 10.1016/j.bmc.2024.117734. Epub 2024 Apr 23. Bioorg Med Chem. 2024. PMID: 38677112

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