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Chronic exposure to excess iron promotes EMT and cancer via p53 loss in pancreatic cancer.
Bhutia YD, Ogura J, Grippo PJ, Torres C, Sato T, Wachtel M, Ramachandran S, Babu E, Sivaprakasam S, Rajasekaran D, Schniers B, On N, Smoot L, Thangaraju M, Gnana-Prakasam JP, Ganapathy V. Bhutia YD, et al. Among authors: rajasekaran d. Asian J Pharm Sci. 2020 Mar;15(2):237-251. doi: 10.1016/j.ajps.2020.02.003. Epub 2020 Mar 5. Asian J Pharm Sci. 2020. PMID: 32373202 Free PMC article.
Small molecule inhibitors of Late SV40 Factor (LSF) abrogate hepatocellular carcinoma (HCC): Evaluation using an endogenous HCC model.
Rajasekaran D, Siddiq A, Willoughby JL, Biagi JM, Christadore LM, Yunes SA, Gredler R, Jariwala N, Robertson CL, Akiel MA, Shen XN, Subler MA, Windle JJ, Schaus SE, Fisher PB, Hansen U, Sarkar D. Rajasekaran D, et al. Oncotarget. 2015 Sep 22;6(28):26266-77. doi: 10.18632/oncotarget.4656. Oncotarget. 2015. PMID: 26313006 Free PMC article.
Insulin-like growth factor-binding protein-7 (IGFBP7): a promising gene therapeutic for hepatocellular carcinoma (HCC).
Chen D, Siddiq A, Emdad L, Rajasekaran D, Gredler R, Shen XN, Santhekadur PK, Srivastava J, Robertson CL, Dmitriev I, Kashentseva EA, Curiel DT, Fisher PB, Sarkar D. Chen D, et al. Among authors: rajasekaran d. Mol Ther. 2013 Apr;21(4):758-66. doi: 10.1038/mt.2012.282. Epub 2013 Jan 15. Mol Ther. 2013. PMID: 23319057 Free PMC article. Retracted.
Genetic deletion of AEG-1 prevents hepatocarcinogenesis.
Robertson CL, Srivastava J, Siddiq A, Gredler R, Emdad L, Rajasekaran D, Akiel M, Shen XN, Guo C, Giashuddin S, Wang XY, Ghosh S, Subler MA, Windle JJ, Fisher PB, Sarkar D. Robertson CL, et al. Among authors: rajasekaran d. Cancer Res. 2014 Nov 1;74(21):6184-93. doi: 10.1158/0008-5472.CAN-14-1357. Epub 2014 Sep 5. Cancer Res. 2014. PMID: 25193383 Free PMC article.
Astrocyte Elevated Gene-1 (AEG-1) Contributes to Non-thyroidal Illness Syndrome (NTIS) Associated with Hepatocellular Carcinoma (HCC).
Srivastava J, Robertson CL, Gredler R, Siddiq A, Rajasekaran D, Akiel MA, Emdad L, Mas V, Mukhopadhyay ND, Fisher PB, Sarkar D. Srivastava J, et al. Among authors: rajasekaran d. J Biol Chem. 2015 Jun 19;290(25):15549-15558. doi: 10.1074/jbc.M115.649707. Epub 2015 May 5. J Biol Chem. 2015. PMID: 25944909 Free PMC article.
Combination of Nanoparticle-Delivered siRNA for Astrocyte Elevated Gene-1 (AEG-1) and All-trans Retinoic Acid (ATRA): An Effective Therapeutic Strategy for Hepatocellular Carcinoma (HCC).
Rajasekaran D, Srivastava J, Ebeid K, Gredler R, Akiel M, Jariwala N, Robertson CL, Shen XN, Siddiq A, Fisher PB, Salem AK, Sarkar D. Rajasekaran D, et al. Bioconjug Chem. 2015 Aug 19;26(8):1651-61. doi: 10.1021/acs.bioconjchem.5b00254. Epub 2015 Jun 25. Bioconjug Chem. 2015. PMID: 26079152 Free PMC article.
Oncogenic Role of SND1 in Development and Progression of Hepatocellular Carcinoma.
Jariwala N, Rajasekaran D, Mendoza RG, Shen XN, Siddiq A, Akiel MA, Robertson CL, Subler MA, Windle JJ, Fisher PB, Sanyal AJ, Sarkar D. Jariwala N, et al. Among authors: rajasekaran d. Cancer Res. 2017 Jun 15;77(12):3306-3316. doi: 10.1158/0008-5472.CAN-17-0298. Epub 2017 Apr 20. Cancer Res. 2017. PMID: 28428278 Free PMC article.
77 results