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Intestinal development and homeostasis require activation and apoptosis of diet-reactive T cells.
Visekruna A, Hartmann S, Sillke YR, Glauben R, Fischer F, Raifer H, Mollenkopf H, Bertrams W, Schmeck B, Klein M, Pagenstecher A, Lohoff M, Jacob R, Pabst O, Bland PW, Luu M, Romero R, Siegmund B, Rajalingam K, Steinhoff U. Visekruna A, et al. Among authors: rajalingam k. J Clin Invest. 2019 Apr 2;129(5):1972-1983. doi: 10.1172/JCI98929. eCollection 2019 Apr 2. J Clin Invest. 2019. PMID: 30939122 Free PMC article.
Selected commensals educate the intestinal vascular and immune system for immunocompetence.
Romero R, Zarzycka A, Preussner M, Fischer F, Hain T, Herrmann JP, Roth K, Keber CU, Suryamohan K, Raifer H, Luu M, Leister H, Bertrams W, Klein M, Shams-Eldin H, Jacob R, Mollenkopf HJ, Rajalingam K, Visekruna A, Steinhoff U. Romero R, et al. Among authors: rajalingam k. Microbiome. 2022 Sep 28;10(1):158. doi: 10.1186/s40168-022-01353-5. Microbiome. 2022. PMID: 36171625 Free PMC article.
ERK3/MAPK6 controls IL-8 production and chemotaxis.
Bogucka K, Pompaiah M, Marini F, Binder H, Harms G, Kaulich M, Klein M, Michel C, Radsak MP, Rosigkeit S, Grimminger P, Schild H, Rajalingam K. Bogucka K, et al. Among authors: rajalingam k. Elife. 2020 Apr 21;9:e52511. doi: 10.7554/eLife.52511. Elife. 2020. PMID: 32314963 Free PMC article.
Protein kinase CK2 enables regulatory T cells to suppress excessive TH2 responses in vivo.
Ulges A, Klein M, Reuter S, Gerlitzki B, Hoffmann M, Grebe N, Staudt V, Stergiou N, Bohn T, Brühl TJ, Muth S, Yurugi H, Rajalingam K, Bellinghausen I, Tuettenberg A, Hahn S, Reißig S, Haben I, Zipp F, Waisman A, Probst HC, Beilhack A, Buchou T, Filhol-Cochet O, Boldyreff B, Breloer M, Jonuleit H, Schild H, Schmitt E, Bopp T. Ulges A, et al. Among authors: rajalingam k. Nat Immunol. 2015 Mar;16(3):267-75. doi: 10.1038/ni.3083. Epub 2015 Jan 19. Nat Immunol. 2015. PMID: 25599562
ARAF suppresses ERBB3 expression and metastasis in a subset of lung cancers.
Mooz J, Riegel K, Ps H, Sadanandam A, Marini F, Klein M, Werner U, Roth W, Wilken-Schmitz A, Tegeder I, Rajalingam K. Mooz J, et al. Among authors: rajalingam k. Sci Adv. 2022 Mar 18;8(11):eabk1538. doi: 10.1126/sciadv.abk1538. Epub 2022 Mar 18. Sci Adv. 2022. PMID: 35302851 Free PMC article.
123 results