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Anti-COX-2 autoantibody is a novel biomarker of immune aplastic anemia.
Kelkka T, Tyster M, Lundgren S, Feng X, Kerr C, Hosokawa K, Huuhtanen J, Keränen M, Patel B, Kawakami T, Maeda Y, Nieminen O, Kasanen T, Aronen P, Yadav B, Rajala H, Nakazawa H, Jaatinen T, Hellström-Lindberg E, Ogawa S, Ishida F, Nishikawa H, Nakao S, Maciejewski J, Young NS, Mustjoki S. Kelkka T, et al. Among authors: rajala h. Leukemia. 2022 Sep;36(9):2317-2327. doi: 10.1038/s41375-022-01654-6. Epub 2022 Aug 5. Leukemia. 2022. PMID: 35927326 Free PMC article.
Somatic mutations in lymphocytes in patients with immune-mediated aplastic anemia.
Lundgren S, Keränen MAI, Kankainen M, Huuhtanen J, Walldin G, Kerr CM, Clemente M, Ebeling F, Rajala H, Brück O, Lähdesmäki H, Hannula S, Hannunen T, Ellonen P, Young NS, Ogawa S, Maciejewski JP, Hellström-Lindberg E, Mustjoki S. Lundgren S, et al. Among authors: rajala h. Leukemia. 2021 May;35(5):1365-1379. doi: 10.1038/s41375-021-01231-3. Epub 2021 Mar 30. Leukemia. 2021. PMID: 33785863 Free PMC article.
Single-cell characterization of leukemic and non-leukemic immune repertoires in CD8+ T-cell large granular lymphocytic leukemia.
Huuhtanen J, Bhattacharya D, Lönnberg T, Kankainen M, Kerr C, Theodoropoulos J, Rajala H, Gurnari C, Kasanen T, Braun T, Teramo A, Zambello R, Herling M, Ishida F, Kawakami T, Salmi M, Loughran T, Maciejewski JP, Lähdesmäki H, Kelkka T, Mustjoki S. Huuhtanen J, et al. Among authors: rajala h. Nat Commun. 2022 Apr 11;13(1):1981. doi: 10.1038/s41467-022-29173-z. Nat Commun. 2022. PMID: 35411050 Free PMC article.
Activating somatic mutations outside the SH2-domain of STAT3 in LGL leukemia.
Andersson E, Kuusanmäki H, Bortoluzzi S, Lagström S, Parsons A, Rajala H, van Adrichem A, Eldfors S, Olson T, Clemente MJ, Laasonen A, Ellonen P, Heckman C, Loughran TP, Maciejewski JP, Mustjoki S. Andersson E, et al. Among authors: rajala h. Leukemia. 2016 May;30(5):1204-8. doi: 10.1038/leu.2015.263. Epub 2015 Sep 30. Leukemia. 2016. PMID: 26419508 Free PMC article. No abstract available.
STAT3 mutations indicate the presence of subclinical T-cell clones in a subset of aplastic anemia and myelodysplastic syndrome patients.
Jerez A, Clemente MJ, Makishima H, Rajala H, Gómez-Seguí I, Olson T, McGraw K, Przychodzen B, Kulasekararaj A, Afable M, Husseinzadeh HD, Hosono N, LeBlanc F, Lagström S, Zhang D, Ellonen P, Tichelli A, Nissen C, Lichtin AE, Wodnar-Filipowicz A, Mufti GJ, List AF, Mustjoki S, Loughran TP Jr, Maciejewski JP. Jerez A, et al. Among authors: rajala h. Blood. 2013 Oct 3;122(14):2453-9. doi: 10.1182/blood-2013-04-494930. Epub 2013 Aug 7. Blood. 2013. PMID: 23926297 Free PMC article.
Somatic mutations in clonally expanded cytotoxic T lymphocytes in patients with newly diagnosed rheumatoid arthritis.
Savola P, Kelkka T, Rajala HL, Kuuliala A, Kuuliala K, Eldfors S, Ellonen P, Lagström S, Lepistö M, Hannunen T, Andersson EI, Khajuria RK, Jaatinen T, Koivuniemi R, Repo H, Saarela J, Porkka K, Leirisalo-Repo M, Mustjoki S. Savola P, et al. Among authors: rajala hl. Nat Commun. 2017 Jun 21;8:15869. doi: 10.1038/ncomms15869. Nat Commun. 2017. PMID: 28635960 Free PMC article.
Immunosuppressive therapy of LGL leukemia: prospective multicenter phase II study by the Eastern Cooperative Oncology Group (E5998).
Loughran TP Jr, Zickl L, Olson TL, Wang V, Zhang D, Rajala HL, Hasanali Z, Bennett JM, Lazarus HM, Litzow MR, Evens AM, Mustjoki S, Tallman MS. Loughran TP Jr, et al. Among authors: rajala hl. Leukemia. 2015 Apr;29(4):886-94. doi: 10.1038/leu.2014.298. Epub 2014 Sep 13. Leukemia. 2015. PMID: 25306898 Free PMC article. Clinical Trial.
36 results