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Noncanonical scaffolding of Gαi and β-arrestin by G protein-coupled receptors.
Smith JS, Pack TF, Inoue A, Lee C, Zheng K, Choi I, Eiger DS, Warman A, Xiong X, Ma Z, Viswanathan G, Levitan IM, Rochelle LK, Staus DP, Snyder JC, Kahsai AW, Caron MG, Rajagopal S. Smith JS, et al. Among authors: rajagopal s. Science. 2021 Mar 12;371(6534):eaay1833. doi: 10.1126/science.aay1833. Epub 2021 Jan 21. Science. 2021. PMID: 33479120 Free PMC article.
Therapeutic potential of β-arrestin- and G protein-biased agonists.
Whalen EJ, Rajagopal S, Lefkowitz RJ. Whalen EJ, et al. Among authors: rajagopal s. Trends Mol Med. 2011 Mar;17(3):126-39. doi: 10.1016/j.molmed.2010.11.004. Epub 2010 Dec 21. Trends Mol Med. 2011. PMID: 21183406 Free PMC article. Review.
Multiple ligand-specific conformations of the β2-adrenergic receptor.
Kahsai AW, Xiao K, Rajagopal S, Ahn S, Shukla AK, Sun J, Oas TG, Lefkowitz RJ. Kahsai AW, et al. Among authors: rajagopal s. Nat Chem Biol. 2011 Aug 21;7(10):692-700. doi: 10.1038/nchembio.634. Nat Chem Biol. 2011. PMID: 21857662 Free PMC article.
GPCR desensitization: Acute and prolonged phases.
Rajagopal S, Shenoy SK. Rajagopal S, et al. Cell Signal. 2018 Jan;41:9-16. doi: 10.1016/j.cellsig.2017.01.024. Epub 2017 Jan 28. Cell Signal. 2018. PMID: 28137506 Free PMC article. Review.
579 results