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849 results

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Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma.
Osman AA, Arslan E, Bartels M, Michikawa C, Lindemann A, Tomczak K, Yu W, Sandulache V, Ma W, Shen L, Wang J, Singh AK, Frederick MJ, Spencer ND, Kovacs J, Heffernan T, Symmans WF, Rai K, Myers JN. Osman AA, et al. Among authors: rai k. Clin Cancer Res. 2023 Apr 3;29(7):1344-1359. doi: 10.1158/1078-0432.CCR-22-2747. Clin Cancer Res. 2023. PMID: 36689560 Free PMC article.
Dual Roles of RNF2 in Melanoma Progression.
Rai K, Akdemir KC, Kwong LN, Fiziev P, Wu CJ, Keung EZ, Sharma S, Samant NS, Williams M, Axelrad JB, Shah A, Yang D, Grimm EA, Barton MC, Milton DR, Heffernan TP, Horner JW, Ekmekcioglu S, Lazar AJ, Ernst J, Chin L. Rai K, et al. Cancer Discov. 2015 Dec;5(12):1314-27. doi: 10.1158/2159-8290.CD-15-0493. Epub 2015 Oct 8. Cancer Discov. 2015. PMID: 26450788 Free PMC article.
TRIM28 and Interacting KRAB-ZNFs Control Self-Renewal of Human Pluripotent Stem Cells through Epigenetic Repression of Pro-differentiation Genes.
Oleksiewicz U, Gładych M, Raman AT, Heyn H, Mereu E, Chlebanowska P, Andrzejewska A, Sozańska B, Samant N, Fąk K, Auguścik P, Kosiński M, Wróblewska JP, Tomczak K, Kulcenty K, Płoski R, Biecek P, Esteller M, Shah PK, Rai K, Wiznerowicz M. Oleksiewicz U, et al. Among authors: rai k. Stem Cell Reports. 2017 Dec 12;9(6):2065-2080. doi: 10.1016/j.stemcr.2017.10.031. Epub 2017 Nov 30. Stem Cell Reports. 2017. PMID: 29198826 Free PMC article.
Enhancer Reprogramming Confers Dependence on Glycolysis and IGF Signaling in KMT2D Mutant Melanoma.
Maitituoheti M, Keung EZ, Tang M, Yan L, Alam H, Han G, Singh AK, Raman AT, Terranova C, Sarkar S, Orouji E, Amin SB, Sharma S, Williams M, Samant NS, Dhamdhere M, Zheng N, Shah T, Shah A, Axelrad JB, Anvar NE, Lin YH, Jiang S, Chang EQ, Ingram DR, Wang WL, Lazar A, Lee MG, Muller F, Wang L, Ying H, Rai K. Maitituoheti M, et al. Among authors: rai k. Cell Rep. 2020 Oct 20;33(3):108293. doi: 10.1016/j.celrep.2020.108293. Cell Rep. 2020. PMID: 33086062 Free PMC article.
Chromatin state dynamics confers specific therapeutic strategies in enhancer subtypes of colorectal cancer.
Orouji E, Raman AT, Singh AK, Sorokin A, Arslan E, Ghosh AK, Schulz J, Terranova C, Jiang S, Tang M, Maitituoheti M, Callahan SC, Barrodia P, Tomczak K, Jiang Y, Jiang Z, Davis JS, Ghosh S, Lee HM, Reyes-Uribe L, Chang K, Liu Y, Chen H, Azhdarinia A, Morris J, Vilar E, Carmon KS, Kopetz SE, Rai K. Orouji E, et al. Among authors: rai k. Gut. 2022 May;71(5):938-949. doi: 10.1136/gutjnl-2020-322835. Epub 2021 May 31. Gut. 2022. PMID: 34059508 Free PMC article.
Reprogramming of bivalent chromatin states in NRAS mutant melanoma suggests PRC2 inhibition as a therapeutic strategy.
Terranova CJ, Tang M, Maitituoheti M, Raman AT, Ghosh AK, Schulz J, Amin SB, Orouji E, Tomczak K, Sarkar S, Oba J, Creasy C, Wu CJ, Khan S, Lazcano R, Wani K, Singh A, Barrodia P, Zhao D, Chen K, Haydu LE, Wang WL, Lazar AJ, Woodman SE, Bernatchez C, Rai K. Terranova CJ, et al. Among authors: rai k. Cell Rep. 2021 Jul 20;36(3):109410. doi: 10.1016/j.celrep.2021.109410. Cell Rep. 2021. PMID: 34289358 Free PMC article.
Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy.
Abbas HA, Hao D, Tomczak K, Barrodia P, Im JS, Reville PK, Alaniz Z, Wang W, Wang R, Wang F, Al-Atrash G, Takahashi K, Ning J, Ding M, Beird HC, Mathews JT, Little L, Zhang J, Basu S, Konopleva M, Marques-Piubelli ML, Solis LM, Parra ER, Lu W, Tamegnon A, Garcia-Manero G, Green MR, Sharma P, Allison JP, Kornblau SM, Rai K, Wang L, Daver N, Futreal A. Abbas HA, et al. Among authors: rai k. Nat Commun. 2021 Oct 18;12(1):6071. doi: 10.1038/s41467-021-26282-z. Nat Commun. 2021. PMID: 34663807 Free PMC article.
849 results