Rai DK - Search Results

1

An oral SARS-CoV-2 M^pro inhibitor clinical candidate for the treatment of COVID-19.

Owen DR, Allerton CMN, Anderson AS, Aschenbrenner L, Avery M, Berritt S, Boras B, Cardin RD, Carlo A, Coffman KJ, Dantonio A, Di L, Eng H, Ferre R, Gajiwala KS, Gibson SA, Greasley SE, Hurst BL, Kadar EP, Kalgutkar AS, Lee JC, Lee J, Liu W, Mason SW, Noell S, Novak JJ, Obach RS, Ogilvie K, Patel NC, Pettersson M, Rai DK, Reese MR, Sammons MF, Sathish JG, Singh RSP, Steppan CM, Stewart AE, Tuttle JB, Updyke L, Verhoest PR, Wei L, Yang Q, Zhu Y. Owen DR, et al. Among authors: rai dk. Science. 2021 Dec 24;374(6575):1586-1593. doi: 10.1126/science.abl4784. Epub 2021 Nov 2. Science. 2021. PMID: 34726479 Free article.

2

Generation of a VeroE6 Pgp gene knock out cell line and its use in SARS-CoV-2 antiviral study.

Zhu Y, Binder J, Yurgelonis I, Rai DK, Lazarro S, Costales C, Kobylarz K, McMonagle P, Steppan CM, Aschenbrenner L, Anderson AS, Cardin RD. Zhu Y, et al. Among authors: rai dk. Antiviral Res. 2022 Dec;208:105429. doi: 10.1016/j.antiviral.2022.105429. Epub 2022 Oct 5. Antiviral Res. 2022. PMID: 36208677 Free PMC article.

3

Repeated exposure to 5D9, an inhibitor of 3D polymerase, effectively limits the replication of foot-and-mouth disease virus in host cells.

Rai DK, Schafer EA, Singh K, McIntosh MA, Sarafianos SG, Rieder E. Rai DK, et al. Antiviral Res. 2013 Jun;98(3):380-5. doi: 10.1016/j.antiviral.2013.03.022. Epub 2013 Apr 8. Antiviral Res. 2013. PMID: 23578728 Free PMC article.

4

Inhibitors of foot and mouth disease virus targeting a novel pocket of the RNA-dependent RNA polymerase.

Durk RC, Singh K, Cornelison CA, Rai DK, Matzek KB, Leslie MD, Schafer E, Marchand B, Adedeji A, Michailidis E, Dorst CA, Moran J, Pautler C, Rodriguez LL, McIntosh MA, Rieder E, Sarafianos SG. Durk RC, et al. Among authors: rai dk. PLoS One. 2010 Dec 21;5(12):e15049. doi: 10.1371/journal.pone.0015049. PLoS One. 2010. PMID: 21203539 Free PMC article.

5

Analysis of the interaction between host factor Sam68 and viral elements during foot-and-mouth disease virus infections.

Rai DK, Lawrence P, Kloc A, Schafer E, Rieder E. Rai DK, et al. Virol J. 2015 Dec 23;12:224. doi: 10.1186/s12985-015-0452-8. Virol J. 2015. PMID: 26695943 Free PMC article.

6

Attenuation of Foot-and-Mouth Disease Virus by Engineered Viral Polymerase Fidelity.

Rai DK, Diaz-San Segundo F, Campagnola G, Keith A, Schafer EA, Kloc A, de Los Santos T, Peersen O, Rieder E. Rai DK, et al. J Virol. 2017 Jul 12;91(15):e00081-17. doi: 10.1128/JVI.00081-17. Print 2017 Aug 1. J Virol. 2017. PMID: 28515297 Free PMC article.

7

Foot-and-mouth disease virus 5'-terminal S fragment is required for replication and modulation of the innate immune response in host cells.

Kloc A, Diaz-San Segundo F, Schafer EA, Rai DK, Kenney M, de Los Santos T, Rieder E. Kloc A, et al. Among authors: rai dk. Virology. 2017 Dec;512:132-143. doi: 10.1016/j.virol.2017.08.036. Virology. 2017. PMID: 28961454 Free article.

8

Residues within the Foot-and-Mouth Disease Virus 3D^pol Nuclear Localization Signal Affect Polymerase Fidelity.

Kloc A, Rai DK, Gladue DP, Schafer E, Kenney M, Rieder E. Kloc A, et al. Among authors: rai dk. J Virol. 2020 Aug 17;94(17):e00833-20. doi: 10.1128/JVI.00833-20. Print 2020 Aug 17. J Virol. 2020. PMID: 32581111 Free PMC article.

9

Role of Jumonji C-domain containing protein 6 (JMJD6) in infectivity of foot-and-mouth disease virus.

Lawrence P, Rai D, Conderino JS, Uddowla S, Rieder E. Lawrence P, et al. Virology. 2016 May;492:38-52. doi: 10.1016/j.virol.2016.02.005. Epub 2016 Feb 19. Virology. 2016. PMID: 26896934 Free article.

10

Homology modeling and analysis of structure predictions of the bovine rhinitis B virus RNA dependent RNA polymerase (RdRp).

Rai DK, Rieder E. Rai DK, et al. Int J Mol Sci. 2012;13(7):8998-9013. doi: 10.3390/ijms13078998. Epub 2012 Jul 19. Int J Mol Sci. 2012. PMID: 22942748 Free PMC article.

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