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Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach.
Krug AK, Kolde R, Gaspar JA, Rempel E, Balmer NV, Meganathan K, Vojnits K, Baquié M, Waldmann T, Ensenat-Waser R, Jagtap S, Evans RM, Julien S, Peterson H, Zagoura D, Kadereit S, Gerhard D, Sotiriadou I, Heke M, Natarajan K, Henry M, Winkler J, Marchan R, Stoppini L, Bosgra S, Westerhout J, Verwei M, Vilo J, Kortenkamp A, Hescheler J, Hothorn L, Bremer S, van Thriel C, Krause KH, Hengstler JG, Rahnenführer J, Leist M, Sachinidis A. Krug AK, et al. Among authors: rahnenfuhrer j. Arch Toxicol. 2013 Jan;87(1):123-43. doi: 10.1007/s00204-012-0967-3. Epub 2012 Nov 21. Arch Toxicol. 2013. PMID: 23179753 Free PMC article.
Test systems of developmental toxicity: state-of-the art and future perspectives.
Leist M, Ringwald A, Kolde R, Bremer S, van Thriel C, Krause KH, Rahnenführer J, Sachinidis A, Hescheler J, Hengstler JG. Leist M, et al. Among authors: rahnenfuhrer j. Arch Toxicol. 2013 Dec;87(12):2037-42. doi: 10.1007/s00204-013-1154-x. Arch Toxicol. 2013. PMID: 24190503 No abstract available.
From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects.
Balmer NV, Klima S, Rempel E, Ivanova VN, Kolde R, Weng MK, Meganathan K, Henry M, Sachinidis A, Berthold MR, Hengstler JG, Rahnenführer J, Waldmann T, Leist M. Balmer NV, et al. Among authors: rahnenfuhrer j. Arch Toxicol. 2014 Jul;88(7):1451-68. doi: 10.1007/s00204-014-1279-6. Epub 2014 Jun 17. Arch Toxicol. 2014. PMID: 24935251 Free PMC article.
Toxicogenomics directory of chemically exposed human hepatocytes.
Grinberg M, Stöber RM, Edlund K, Rempel E, Godoy P, Reif R, Widera A, Madjar K, Schmidt-Heck W, Marchan R, Sachinidis A, Spitkovsky D, Hescheler J, Carmo H, Arbo MD, van de Water B, Wink S, Vinken M, Rogiers V, Escher S, Hardy B, Mitic D, Myatt G, Waldmann T, Mardinoglu A, Damm G, Seehofer D, Nüssler A, Weiss TS, Oberemm A, Lampen A, Schaap MM, Luijten M, van Steeg H, Thasler WE, Kleinjans JC, Stierum RH, Leist M, Rahnenführer J, Hengstler JG. Grinberg M, et al. Among authors: rahnenfuhrer j. Arch Toxicol. 2014 Dec;88(12):2261-87. doi: 10.1007/s00204-014-1400-x. Epub 2014 Nov 16. Arch Toxicol. 2014. PMID: 25399406
A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors.
Rempel E, Hoelting L, Waldmann T, Balmer NV, Schildknecht S, Grinberg M, Das Gaspar JA, Shinde V, Stöber R, Marchan R, van Thriel C, Liebing J, Meisig J, Blüthgen N, Sachinidis A, Rahnenführer J, Hengstler JG, Leist M. Rempel E, et al. Among authors: rahnenfuhrer j. Arch Toxicol. 2015 Sep;89(9):1599-618. doi: 10.1007/s00204-015-1573-y. Epub 2015 Aug 14. Arch Toxicol. 2015. PMID: 26272509 Free PMC article.
170 results