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Time-resolved crystallography captures light-driven DNA repair.
Christou NE, Apostolopoulou V, Melo DVM, Ruppert M, Fadini A, Henkel A, Sprenger J, Oberthuer D, Günther S, Pateras A, Rahmani Mashhour A, Yefanov OM, Galchenkova M, Reinke PYA, Kremling V, Scheer TES, Lange ER, Middendorf P, Schubert R, De Zitter E, Lumbao-Conradson K, Herrmann J, Rahighi S, Kunavar A, Beale EV, Beale JH, Cirelli C, Johnson PJM, Dworkowski F, Ozerov D, Bertrand Q, Wranik M, Bacellar C, Bajt S, Wakatsuki S, Sellberg JA, Huse N, Turk D, Chapman HN, Lane TJ. Christou NE, et al. Among authors: rahmani mashhour a. Science. 2023 Dec;382(6674):1015-1020. doi: 10.1126/science.adj4270. Epub 2023 Nov 30. Science. 2023. PMID: 38033070
Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated from natural crystals using MHz-SFX.
Williamson LJ, Galchenkova M, Best HL, Bean RJ, Munke A, Awel S, Pena G, Knoska J, Schubert R, Dörner K, Park HW, Bideshi DK, Henkel A, Kremling V, Klopprogge B, Lloyd-Evans E, Young MT, Valerio J, Kloos M, Sikorski M, Mills G, Bielecki J, Kirkwood H, Kim C, de Wijn R, Lorenzen K, Xavier PL, Rahmani Mashhour A, Gelisio L, Yefanov O, Mancuso AP, Federici BA, Chapman HN, Crickmore N, Rizkallah PJ, Berry C, Oberthür D. Williamson LJ, et al. Among authors: rahmani mashhour a. Proc Natl Acad Sci U S A. 2023 Dec 5;120(49):e2203241120. doi: 10.1073/pnas.2203241120. Epub 2023 Nov 28. Proc Natl Acad Sci U S A. 2023. PMID: 38015839 Free PMC article.
Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections.
Reinke PYA, de Souza EE, Günther S, Falke S, Lieske J, Ewert W, Loboda J, Herrmann A, Rahmani Mashhour A, Karničar K, Usenik A, Lindič N, Sekirnik A, Botosso VF, Santelli GMM, Kapronezai J, de Araújo MV, Silva-Pereira TT, Filho AFS, Tavares MS, Flórez-Álvarez L, de Oliveira DBL, Durigon EL, Giaretta PR, Heinemann MB, Hauser M, Seychell B, Böhler H, Rut W, Drag M, Beck T, Cox R, Chapman HN, Betzel C, Brehm W, Hinrichs W, Ebert G, Latham SL, Guimarães AMS, Turk D, Wrenger C, Meents A. Reinke PYA, et al. Among authors: rahmani mashhour a. Commun Biol. 2023 Oct 18;6(1):1058. doi: 10.1038/s42003-023-05317-9. Commun Biol. 2023. PMID: 37853179 Free PMC article.