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Optimized low-dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatment.
Zoetemelk M, Ramzy GM, Rausch M, Koessler T, van Beijnum JR, Weiss A, Mieville V, Piersma SR, de Haas RR, Delucinge-Vivier C, Andres A, Toso C, Henneman AA, Ragusa S, Petrova TV, Docquier M, McKee TA, Jimenez CR, Daali Y, Griffioen AW, Rubbia-Brandt L, Dietrich PY, Nowak-Sliwinska P. Zoetemelk M, et al. Among authors: ragusa s. Mol Oncol. 2020 Nov;14(11):2894-2919. doi: 10.1002/1878-0261.12797. Epub 2020 Oct 5. Mol Oncol. 2020. PMID: 33021054 Free PMC article.
PROX1 promotes metabolic adaptation and fuels outgrowth of Wnt(high) metastatic colon cancer cells.
Ragusa S, Cheng J, Ivanov KI, Zangger N, Ceteci F, Bernier-Latmani J, Milatos S, Joseph JM, Tercier S, Bouzourene H, Bosman FT, Letovanec I, Marra G, Gonzalez M, Cammareri P, Sansom OJ, Delorenzi M, Petrova TV. Ragusa S, et al. Cell Rep. 2014 Sep 25;8(6):1957-1973. doi: 10.1016/j.celrep.2014.08.041. Epub 2014 Sep 18. Cell Rep. 2014. PMID: 25242332 Free article.
Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice.
Ragusa S, Prat-Luri B, González-Loyola A, Nassiri S, Squadrito ML, Guichard A, Cavin S, Gjorevski N, Barras D, Marra G, Lutolf MP, Perentes J, Corse E, Bianchi R, Wetterwald L, Kim J, Oliver G, Delorenzi M, De Palma M, Petrova TV. Ragusa S, et al. J Clin Invest. 2020 Mar 2;130(3):1199-1216. doi: 10.1172/JCI129558. J Clin Invest. 2020. PMID: 32015230 Free PMC article.
Apelin-driven endothelial cell migration sustains intestinal progenitor cells and tumor growth.
Bernier-Latmani J, Cisarovsky C, Mahfoud S, Ragusa S, Dupanloup I, Barras D, Renevey F, Nassiri S, Anderle P, Squadrito ML, Siegert S, Davanture S, González-Loyola A, Fournier N, Luther SA, Benedito R, Valet P, Zhou B, De Palma M, Delorenzi M, Sempoux C, Petrova TV. Bernier-Latmani J, et al. Among authors: ragusa s. Nat Cardiovasc Res. 2022 May;1(5):476-490. doi: 10.1038/s44161-022-00061-5. Epub 2022 May 16. Nat Cardiovasc Res. 2022. PMID: 35602406 Free PMC article.
The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance.
Vannini N, Campos V, Girotra M, Trachsel V, Rojas-Sutterlin S, Tratwal J, Ragusa S, Stefanidis E, Ryu D, Rainer PY, Nikitin G, Giger S, Li TY, Semilietof A, Oggier A, Yersin Y, Tauzin L, Pirinen E, Cheng WC, Ratajczak J, Canto C, Ehrbar M, Sizzano F, Petrova TV, Vanhecke D, Zhang L, Romero P, Nahimana A, Cherix S, Duchosal MA, Ho PC, Deplancke B, Coukos G, Auwerx J, Lutolf MP, Naveiras O. Vannini N, et al. Among authors: ragusa s. Cell Stem Cell. 2019 Mar 7;24(3):405-418.e7. doi: 10.1016/j.stem.2019.02.012. Cell Stem Cell. 2019. PMID: 30849366 Free article.
DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport.
Bernier-Latmani J, Cisarovsky C, Demir CS, Bruand M, Jaquet M, Davanture S, Ragusa S, Siegert S, Dormond O, Benedito R, Radtke F, Luther SA, Petrova TV. Bernier-Latmani J, et al. Among authors: ragusa s. J Clin Invest. 2015 Nov 3;125(12):4572-86. doi: 10.1172/JCI82045. J Clin Invest. 2015. PMID: 26529256 Free PMC article.
The CD33xCD123xCD70 Multispecific CD3-Engaging DARPin MP0533 Induces Selective T Cell-Mediated Killing of AML Leukemic Stem Cells.
Bianchi M, Reichen C, Croset A, Fischer S, Eggenschwiler A, Grübler Y, Marpakwar R, Looser T, Spitzli P, Herzog C, Villemagne D, Schiegg D, Abduli L, Iss C, Neculcea A, Franchini M, Lekishvili T, Ragusa S, Zitt C, Kaufmann Y, Auge A, Hänggi M, Ali W, Frasconi TM, Wullschleger S, Schlegel I, Matzner M, Lüthi U, Schlereth B, Dawson KM, Kirkin V, Ochsenbein AF, Grimm S, Reschke N, Riether C, Steiner D, Leupin N, Goubier A. Bianchi M, et al. Among authors: ragusa s. Cancer Immunol Res. 2024 Apr 29. doi: 10.1158/2326-6066.CIR-23-0692. Online ahead of print. Cancer Immunol Res. 2024. PMID: 38683145 Free article.
96 results