Rafidi K - Search Results

1

4-methylpteridinones as orally active and selective PI3K/mTOR dual inhibitors.

Liu KK, Bagrodia S, Bailey S, Cheng H, Chen H, Gao L, Greasley S, Hoffman JE, Hu Q, Johnson TO, Knighton D, Liu Z, Marx MA, Nambu MD, Ninkovic S, Pascual B, Rafidi K, Rodgers CM, Smith GL, Sun S, Wang H, Yang A, Yuan J, Zou A. Liu KK, et al. Among authors: rafidi k. Bioorg Med Chem Lett. 2010 Oct 15;20(20):6096-9. doi: 10.1016/j.bmcl.2010.08.045. Epub 2010 Aug 14. Bioorg Med Chem Lett. 2010. PMID: 20817449

2

Quinazolines with intra-molecular hydrogen bonding scaffold (iMHBS) as PI3K/mTOR dual inhibitors.

Liu KK, Huang X, Bagrodia S, Chen JH, Greasley S, Cheng H, Sun S, Knighton D, Rodgers C, Rafidi K, Zou A, Xiao J, Yan S. Liu KK, et al. Among authors: rafidi k. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1270-4. doi: 10.1016/j.bmcl.2010.12.026. Epub 2010 Dec 10. Bioorg Med Chem Lett. 2011. PMID: 21269826

3

PF-04691502, a potent and selective oral inhibitor of PI3K and mTOR kinases with antitumor activity.

Yuan J, Mehta PP, Yin MJ, Sun S, Zou A, Chen J, Rafidi K, Feng Z, Nickel J, Engebretsen J, Hallin J, Blasina A, Zhang E, Nguyen L, Sun M, Vogt PK, McHarg A, Cheng H, Christensen JG, Kan JL, Bagrodia S. Yuan J, et al. Among authors: rafidi k. Mol Cancer Ther. 2011 Nov;10(11):2189-99. doi: 10.1158/1535-7163.MCT-11-0185. Epub 2011 Jul 12. Mol Cancer Ther. 2011. PMID: 21750219

4

Discovery and pharmacologic characterization of CP-724,714, a selective ErbB2 tyrosine kinase inhibitor.

Jani JP, Finn RS, Campbell M, Coleman KG, Connell RD, Currier N, Emerson EO, Floyd E, Harriman S, Kath JC, Morris J, Moyer JD, Pustilnik LR, Rafidi K, Ralston S, Rossi AM, Steyn SJ, Wagner L, Winter SM, Bhattacharya SK. Jani JP, et al. Among authors: rafidi k. Cancer Res. 2007 Oct 15;67(20):9887-93. doi: 10.1158/0008-5472.CAN-06-3559. Cancer Res. 2007. PMID: 17942920

5

Phosphorylation of serine residues in histidine-tag sequences attached to recombinant protein kinases: a cause of heterogeneity in mass and complications in function.

Du P, Loulakis P, Luo C, Mistry A, Simons SP, LeMotte PK, Rajamohan F, Rafidi K, Coleman KG, Geoghegan KF, Xie Z. Du P, et al. Among authors: rafidi k. Protein Expr Purif. 2005 Dec;44(2):121-9. doi: 10.1016/j.pep.2005.04.018. Protein Expr Purif. 2005. PMID: 15946859

6

Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta.

Garofalo RS, Orena SJ, Rafidi K, Torchia AJ, Stock JL, Hildebrandt AL, Coskran T, Black SC, Brees DJ, Wicks JR, McNeish JD, Coleman KG. Garofalo RS, et al. Among authors: rafidi k. J Clin Invest. 2003 Jul;112(2):197-208. doi: 10.1172/JCI16885. Epub 2003 Jul 3. J Clin Invest. 2003. PMID: 12843127 Free PMC article.

7

Maspin, a serpin with tumor-suppressing activity in human mammary epithelial cells.

Zou Z, Anisowicz A, Hendrix MJ, Thor A, Neveu M, Sheng S, Rafidi K, Seftor E, Sager R. Zou Z, et al. Among authors: rafidi k. Science. 1994 Jan 28;263(5146):526-9. doi: 10.1126/science.8290962. Science. 1994. PMID: 8290962

8

Characterization of the chicken osteopontin-encoding gene.

Rafidi K, Simkina I, Johnson E, Moore MA, Gerstenfeld LC. Rafidi K, et al. Gene. 1994 Mar 25;140(2):163-9. doi: 10.1016/0378-1119(94)90540-1. Gene. 1994. PMID: 8144023

9

Characterization of a cDNA for chicken osteopontin: expression during bone development, osteoblast differentiation, and tissue distribution.

Moore MA, Gotoh Y, Rafidi K, Gerstenfeld LC. Moore MA, et al. Among authors: rafidi k. Biochemistry. 1991 Mar 5;30(9):2501-8. doi: 10.1021/bi00223a029. Biochemistry. 1991. PMID: 2001376

10

Characterization of an avian bone sialoprotein (BSP) cDNA: comparisons to mammalian BSP and identification of conserved structural domains.

Yang R, Gotoh Y, Moore MA, Rafidi K, Gerstenfeld LC. Yang R, et al. Among authors: rafidi k. J Bone Miner Res. 1995 Apr;10(4):632-40. doi: 10.1002/jbmr.5650100417. J Bone Miner Res. 1995. PMID: 7610935 Free article.

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