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EROS is a selective chaperone regulating the phagocyte NADPH oxidase and purinergic signalling.
Randzavola LO, Mortimer PM, Garside E, Dufficy ER, Schejtman A, Roumelioti G, Yu L, Pardo M, Spirohn K, Tolley C, Brandt C, Harcourt K, Nichols E, Nahorski M, Woods G, Williamson JC, Suresh S, Sowerby JM, Matsumoto M, Santos CXC, Kiar CS, Mukhopadhyay S, Rae WM, Dougan GJ, Grainger J, Lehner PJ, Calderwood MA, Choudhary J, Clare S, Speak A, Santilli G, Bateman A, Smith KGC, Magnani F, Thomas DC. Randzavola LO, et al. Among authors: rae wm. Elife. 2022 Nov 24;11:e76387. doi: 10.7554/eLife.76387. Elife. 2022. PMID: 36421765 Free PMC article.
A novel mutation in EROS (CYBC1) causes chronic granulomatous disease.
Mortimer PM, Nichols E, Thomas J, Shanbhag R, Singh N, Coomber EL, Malik TH, Pickering MC, Randzavola L, Rae W, Bhattad S, Thomas DC. Mortimer PM, et al. Clin Immunol. 2023 Oct;255:109761. doi: 10.1016/j.clim.2023.109761. Epub 2023 Sep 8. Clin Immunol. 2023. PMID: 37673227
B cell receptor repertoire kinetics after SARS-CoV-2 infection and vaccination.
Kotagiri P, Mescia F, Rae WM, Bergamaschi L, Tuong ZK, Turner L, Hunter K, Gerber PP, Hosmillo M; Cambridge Institute of Therapeutic Immunology and Infectious Disease-National Institute of Health Research (CITIID-NIHR) COVID BioResource Collaboration; Hess C, Clatworthy MR, Goodfellow IG, Matheson NJ, McKinney EF, Wills MR, Gupta RK, Bradley JR, Bashford-Rogers RJM, Lyons PA, Smith KGC. Kotagiri P, et al. Among authors: rae wm. Cell Rep. 2022 Feb 15;38(7):110393. doi: 10.1016/j.celrep.2022.110393. Epub 2022 Jan 31. Cell Rep. 2022. PMID: 35143756 Free PMC article.