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PHD1 regulates p53-mediated colorectal cancer chemoresistance.
Deschoemaeker S, Di Conza G, Lilla S, Martín-Pérez R, Mennerich D, Boon L, Hendrikx S, Maddocks OD, Marx C, Radhakrishnan P, Prenen H, Schneider M, Myllyharju J, Kietzmann T, Vousden KH, Zanivan S, Mazzone M. Deschoemaeker S, et al. Among authors: radhakrishnan p. EMBO Mol Med. 2015 Oct;7(10):1350-65. doi: 10.15252/emmm.201505492. EMBO Mol Med. 2015. PMID: 26290450 Free PMC article.
Loss of the oxygen sensor PHD3 enhances the innate immune response to abdominal sepsis.
Kiss J, Mollenhauer M, Walmsley SR, Kirchberg J, Radhakrishnan P, Niemietz T, Dudda J, Steinert G, Whyte MK, Carmeliet P, Mazzone M, Weitz J, Schneider M. Kiss J, et al. Among authors: radhakrishnan p. J Immunol. 2012 Aug 15;189(4):1955-65. doi: 10.4049/jimmunol.1103471. Epub 2012 Jul 11. J Immunol. 2012. PMID: 22786772 Free PMC article.
Bcl-xL is an oncogenic driver in colorectal cancer.
Scherr AL, Gdynia G, Salou M, Radhakrishnan P, Duglova K, Heller A, Keim S, Kautz N, Jassowicz A, Elssner C, He YW, Jaeger D, Heikenwalder M, Schneider M, Weber A, Roth W, Schulze-Bergkamen H, Koehler BC. Scherr AL, et al. Among authors: radhakrishnan p. Cell Death Dis. 2016 Aug 18;7(8):e2342. doi: 10.1038/cddis.2016.233. Cell Death Dis. 2016. PMID: 27537525 Free PMC article.
Hydroxylase inhibition regulates inflammation-induced intestinal fibrosis through the suppression of ERK-mediated TGF-β1 signaling. [corrected].
Manresa MC, Tambuwala MM, Radhakrishnan P, Harnoss JM, Brown E, Cavadas MA, Keogh CE, Cheong A, Barrett KE, Cummins EP, Schneider M, Taylor CT. Manresa MC, et al. Among authors: radhakrishnan p. Am J Physiol Gastrointest Liver Physiol. 2016 Dec 1;311(6):G1076-G1090. doi: 10.1152/ajpgi.00229.2016. Epub 2016 Oct 27. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27789456 Free article.
Pharmacological HIF-inhibition attenuates postoperative adhesion formation.
Strowitzki MJ, Ritter AS, Radhakrishnan P, Harnoss JM, Opitz VM, Biller M, Wehrmann J, Keppler U, Scheer J, Wallwiener M, Schmidt T, Ulrich A, Schneider M. Strowitzki MJ, et al. Among authors: radhakrishnan p. Sci Rep. 2017 Oct 13;7(1):13151. doi: 10.1038/s41598-017-13638-z. Sci Rep. 2017. PMID: 29030625 Free PMC article.
205 results