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CD4+ T cell calibration of antigen-presenting cells optimizes antiviral CD8+ T cell immunity.
Gressier E, Schulte-Schrepping J, Petrov L, Brumhard S, Stubbemann P, Hiller A, Obermayer B, Spitzer J, Kostevc T, Whitney PG, Bachem A, Odainic A, van de Sandt C, Nguyen THO, Ashhurst T, Wilson K, Oates CVL, Gearing LJ, Meischel T, Hochheiser K, Greyer M, Clarke M, Kreutzenbeck M, Gabriel SS, Kastenmüller W, Kurts C, Londrigan SL, Kallies A, Kedzierska K, Hertzog PJ, Latz E, Chen YE, Radford KJ, Chopin M, Schroeder J, Kurth F, Gebhardt T, Sander LE, Sawitzki B, Schultze JL, Schmidt SV, Bedoui S. Gressier E, et al. Among authors: radford kj. Nat Immunol. 2023 Jun;24(6):979-990. doi: 10.1038/s41590-023-01517-x. Epub 2023 May 15. Nat Immunol. 2023. PMID: 37188942
T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex.
Beringer DX, Kleijwegt FS, Wiede F, van der Slik AR, Loh KL, Petersen J, Dudek NL, Duinkerken G, Laban S, Joosten A, Vivian JP, Chen Z, Uldrich AP, Godfrey DI, McCluskey J, Price DA, Radford KJ, Purcell AW, Nikolic T, Reid HH, Tiganis T, Roep BO, Rossjohn J. Beringer DX, et al. Among authors: radford kj. Nat Immunol. 2015 Nov;16(11):1153-61. doi: 10.1038/ni.3271. Epub 2015 Oct 5. Nat Immunol. 2015. PMID: 26437244
Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate naïve and memory WT1-specific CD8+ T cells.
Pearson FE, Tullett KM, Leal-Rojas IM, Haigh OL, Masterman KA, Walpole C, Bridgeman JS, McLaren JE, Ladell K, Miners K, Llewellyn-Lacey S, Price DA, Tunger A, Schmitz M, Miles JJ, Lahoud MH, Radford KJ. Pearson FE, et al. Among authors: radford kj. Clin Transl Immunology. 2020 Jun 12;9(6):e1141. doi: 10.1002/cti2.1141. eCollection 2020. Clin Transl Immunology. 2020. PMID: 32547743 Free PMC article.
Human CLEC9A antibodies deliver NY-ESO-1 antigen to CD141+ dendritic cells to activate naïve and memory NY-ESO-1-specific CD8+ T cells.
Masterman KA, Haigh OL, Tullett KM, Leal-Rojas IM, Walpole C, Pearson FE, Cebon J, Schmidt C, O'Brien L, Rosendahl N, Daraj G, Caminschi I, Gschweng EH, Hollis RP, Kohn DB, Lahoud MH, Radford KJ. Masterman KA, et al. Among authors: radford kj. J Immunother Cancer. 2020 Jul;8(2):e000691. doi: 10.1136/jitc-2020-000691. J Immunother Cancer. 2020. PMID: 32737142 Free PMC article.
Elucidating the Motif for CpG Oligonucleotide Binding to the Dendritic Cell Receptor DEC-205 Leads to Improved Adjuvants for Liver-Resident Memory.
Li J, Panetta F, O'Keeffe M, Leal Rojas IM, Radford KJ, Zhang JG, Fernandez-Ruiz D, Davey GM, Gully BS, Tullett KM, Rossjohn J, Berry R, Lee CN, Lahoud MH, Heath WR, Caminschi I. Li J, et al. Among authors: radford kj. J Immunol. 2021 Oct 1;207(7):1836-1847. doi: 10.4049/jimmunol.2001153. Epub 2021 Sep 3. J Immunol. 2021. PMID: 34479944
60 results