Radda GK - Search Results

1

Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression.

Ericksen RE, Lim SL, McDonnell E, Shuen WH, Vadiveloo M, White PJ, Ding Z, Kwok R, Lee P, Radda GK, Toh HC, Hirschey MD, Han W. Ericksen RE, et al. Among authors: radda gk. Cell Metab. 2019 May 7;29(5):1151-1165.e6. doi: 10.1016/j.cmet.2018.12.020. Epub 2019 Jan 17. Cell Metab. 2019. PMID: 30661928 Free PMC article.

2

Downregulating serine hydroxymethyltransferase 2 (SHMT2) suppresses tumorigenesis in human hepatocellular carcinoma.

Woo CC, Chen WC, Teo XQ, Radda GK, Lee PT. Woo CC, et al. Among authors: radda gk. Oncotarget. 2016 Aug 16;7(33):53005-53017. doi: 10.18632/oncotarget.10415. Oncotarget. 2016. PMID: 27391339 Free PMC article.

3

In vivo hyperpolarized carbon-13 magnetic resonance spectroscopy reveals increased pyruvate carboxylase flux in an insulin-resistant mouse model.

Lee P, Leong W, Tan T, Lim M, Han W, Radda GK. Lee P, et al. Among authors: radda gk. Hepatology. 2013 Feb;57(2):515-24. doi: 10.1002/hep.26028. Epub 2013 Jan 10. Hepatology. 2013. PMID: 22911492

4

Robust hyperpolarized (13)C metabolic imaging with selective non-excitation of pyruvate (SNEP).

Chen WC, Teo XQ, Lee MY, Radda GK, Lee P. Chen WC, et al. Among authors: radda gk. NMR Biomed. 2015 Aug;28(8):1021-30. doi: 10.1002/nbm.3346. Epub 2015 Jun 28. NMR Biomed. 2015. PMID: 26119950

5

Increased lipolysis and energy expenditure in a mouse model with severely impaired glucagon secretion.

Lou PH, Gustavsson N, Wang Y, Radda GK, Han W. Lou PH, et al. Among authors: radda gk. PLoS One. 2011;6(10):e26671. doi: 10.1371/journal.pone.0026671. Epub 2011 Oct 27. PLoS One. 2011. PMID: 22046328 Free PMC article.

6

FoxO1 negatively regulates leptin-induced POMC transcription through its direct interaction with STAT3.

Ma W, Fuentes G, Shi X, Verma C, Radda GK, Han W. Ma W, et al. Among authors: radda gk. Biochem J. 2015 Mar 1;466(2):291-8. doi: 10.1042/BJ20141109. Biochem J. 2015. PMID: 25510553

7

A new hyperpolarized ¹³C ketone body probe reveals an increase in acetoacetate utilization in the diabetic rat heart.

Abdurrachim D, Woo CC, Teo XQ, Chan WX, Radda GK, Lee PTH. Abdurrachim D, et al. Among authors: radda gk. Sci Rep. 2019 Apr 2;9(1):5532. doi: 10.1038/s41598-019-39378-w. Sci Rep. 2019. PMID: 30940842 Free PMC article.

8

Suppression of adipogenesis by pathogenic seipin mutant is associated with inflammatory response.

Qiu W, Wee K, Takeda K, Lim X, Sugii S, Radda GK, Han W. Qiu W, et al. Among authors: radda gk. PLoS One. 2013;8(3):e57874. doi: 10.1371/journal.pone.0057874. Epub 2013 Mar 8. PLoS One. 2013. PMID: 23520483 Free PMC article.

9

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse model.

Bard-Chapeau EA, Nguyen AT, Rust AG, Sayadi A, Lee P, Chua BQ, New LS, de Jong J, Ward JM, Chin CK, Chew V, Toh HC, Abastado JP, Benoukraf T, Soong R, Bard FA, Dupuy AJ, Johnson RL, Radda GK, Chan EC, Wessels LF, Adams DJ, Jenkins NA, Copeland NG. Bard-Chapeau EA, et al. Among authors: radda gk. Nat Genet. 2014 Jan;46(1):24-32. doi: 10.1038/ng.2847. Epub 2013 Dec 8. Nat Genet. 2014. PMID: 24316982 Free PMC article.

10

Motor neuron degeneration in a mouse model of seipinopathy.

Guo J, Qiu W, Soh SL, Wei S, Radda GK, Ong WY, Pang ZP, Han W. Guo J, et al. Among authors: radda gk. Cell Death Dis. 2013 Mar 7;4(3):e535. doi: 10.1038/cddis.2013.64. Cell Death Dis. 2013. PMID: 23470542 Free PMC article.

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